1. Gene
  2. Hspa9 - heat shock protein 9 Gene

Hspa9 - heat shock protein 9 Gene

种属: Mus musculus

同用名: Csa; Mot2; 74kDa; Grp75; Hsc74; Hsp74; Mot-2; Pbp74; Hsp74a; Hspa9a; Mthsp70; Mortalin

基因 ID: 15526 | 基因类型: protein coding

关于 Hspa9

功能概要

Enables enzyme binding activity. Involved in iron-sulfur cluster assembly; negative regulation of hematopoietic stem cell differentiation; and negative regulation of hemopoiesis. Acts upstream of or within protein export from nucleus. Located in mitochondrial matrix. Is expressed in blastocyst-stage conceptus; early embryo; germ cell of gonad; heart; and liver. Human ortholog(s) of this gene implicated in Parkinson's disease and autosomal dominant sideroblastic anemia 4. Orthologous to human HSPA9 (heat shock protein family A (HSP70) member 9). [provided by Alliance of Genome Resources, Apr 2022]

Hspa9 基因产物(1)

mRNA Protein Name
NM_010481.2 NP_034611.2 stress-70 protein, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
12646231 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11900485 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in iron-sulfur cluster assembly IMP
IMP: 通过突变表型推断
26702583 MGI
involved in negative regulation of hematopoietic stem cell differentiation IMP
IMP: 通过突变表型推断
21123823 MGI
involved in negative regulation of hemopoiesis IMP
IMP: 通过突变表型推断
21123823 MGI
acts upstream of or within protein export from nucleus IDA
IDA: 通过直接分析推断
11900485 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrial matrix IDA
IDA: 通过直接分析推断
29913563 MGI
located in mitochondrial matrix IDA
IDA: 通过直接分析推断
11092755 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
12931191 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

stress-70 protein, mitochondrial

75 kDa glucose-regulated protein

C3H-specific antigen

GRP-75

heat shock 70 kDa protein 9

heat shock protein 9A

heat shock protein cognate 74

heat shock protein, 74 kDa, A

heat shock protein, A

p66 MOT

peptide-binding protein 74

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hspa9 NCBI NCBI:3313