2. Gene
  3. Htr2b - 5-hydroxytryptamine (serotonin) receptor 2B Gene

Htr2b - 5-hydroxytryptamine (serotonin) receptor 2B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 5-HT2B; 5-HT-2B; 5-HT-2F

基因 ID: 15559 | 基因类型: protein coding

关于 Htr2b

功能概要

Enables G protein-coupled serotonin receptor activity; GTPase activator activity; and serotonin binding activity. Involved in several processes, including ERK1 and ERK2 cascade; cellular response to temperature stimulus; and protein kinase C-activating G protein-coupled receptor signaling pathway. Acts upstream of or within heart development. Located in cytoplasm and plasma membrane. Part of G protein-coupled serotonin receptor complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; reproductive system; and sensory organ. Used to study hypertrophic cardiomyopathy. Orthologous to human HTR2B (5-hydroxytryptamine receptor 2B). [provided by Alliance of Genome Resources, Apr 2022]

Htr2b 基因产物(1)

mRNA Protein Name
NM_008311.3 NP_032337.2 5-hydroxytryptamine receptor 2B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled serotonin receptor activity IDA
IDA: 通过直接分析推断
17325130 MGI
enables GTPase activator activity IMP
IMP: 通过突变表型推断
8621713 MGI
enables serotonin binding IDA
IDA: 通过直接分析推断
17325130 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
8621713 MGI
involved in cardiac muscle hypertrophy IMP
IMP: 通过突变表型推断
19023134 MGI
involved in embryonic morphogenesis IMP
IMP: 通过突变表型推断
9165122 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
10944220 MGI
involved in heart morphogenesis IMP
IMP: 通过突变表型推断
9165122 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
9165122 MGI
involved in neural crest cell differentiation IMP
IMP: 通过突变表型推断
9165122 MGI
involved in neural crest cell migration IMP
IMP: 通过突变表型推断
9165122 MGI
involved in phospholipase C-activating serotonin receptor signaling pathway IMP
IMP: 通过突变表型推断
17325130 MGI
involved in positive regulation of cell division IMP
IMP: 通过突变表型推断
8621713 MGI
involved in positive regulation of cytokine production IMP
IMP: 通过突变表型推断
19023134 MGI
involved in positive regulation of endothelial cell proliferation IMP
IMP: 通过突变表型推断
19308295 MGI
involved in regulation of behavior IMP
IMP: 通过突变表型推断
21179162 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of G protein-coupled serotonin receptor complex IDA
IDA: 通过直接分析推断
17325130 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
17325130 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
17325130 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

5-hydroxytryptamine receptor 2B

NP75 protein

serotonin receptor 2B

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-169229 GM-60186 Inhibitor / 否
HY-RS06468 HTR2B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19011 Htr2b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25500 Htr2b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Htr2b NCBI NCBI:3357
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z