Itga2 - integrin alpha 2 Gene

种属: Mus musculus

同用名: DX5; GPIa; CD49B

关于 Itga2

功能概要

Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell migration; and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; artery disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); and von Willebrand's disease (multiple). Orthologous to human ITGA2 (Integrin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]