2. Gene
  3. Itga2b - integrin alpha 2b Gene

Itga2b - integrin alpha 2b Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CD41; CD41B; GpIIb; alphaIIb

基因 ID: 16399 | 基因类型: protein coding

关于 Itga2b

功能概要

Enables extracellular matrix binding activity. Acts upstream of or within cell-matrix adhesion. Located in external side of plasma membrane and focal adhesion. Is expressed in several structures, including early conceptus; genitourinary system; gut; hematopoietic system; and liver. Used to study platelet-type bleeding disorder 16. Human ortholog(s) of this gene implicated in Glanzmann's thrombasthenia; platelet-type bleeding disorder 16; thrombocytopenia; and von Willebrand's disease 1. Orthologous to human ITGA2B (Integrin subunit alpha 2b). [provided by Alliance of Genome Resources, Apr 2022]

Itga2b 基因产物(1)

mRNA Protein Name
NM_010575.2 NP_034705.2 integrin alpha-IIb precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables extracellular matrix binding IMP
IMP: 通过突变表型推断
15031111 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell-matrix adhesion IMP
IMP: 通过突变表型推断
15031111 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
14751927 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
12900455 MGI
located in focal adhesion IDA
IDA: 通过直接分析推断
15031111 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

integrin alpha-IIb

GP IIb

GPalpha IIb

alpha IIb

platelet glycoprotein IIb of IIb/II Ia complex

platelet membrane glycoprotein IIb

Itga2b 抗体

目录号 产品名 应用 反应物种
HY-P86806 CD41 Antibody (YA6499) IHC-P, FC, ICC/IF Mouse

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06949 ITGA2B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19782 Itga2b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26279 Itga2b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itga2b NCBI NCBI:3674
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