1. Gene
  2. Krt17 - keratin 17 Gene

Krt17 - keratin 17 Gene

种属: Mus musculus

同用名: K17; Krt1-17

基因 ID: 16667 | 基因类型: protein coding

关于 Krt17

功能概要

The protein encoded by this gene is a member of the type I keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The encoded protein is a cytokeratin required for the normal growth of hair follicles and may act in psoriasis as an immunopathogenic autoantigen. [provided by RefSeq, Sep 2015]

Krt17 基因产物(1)

mRNA Protein Name
NM_010663.3 NP_034793.1 keratin, type I cytoskeletal 17
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16702408 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in hair follicle morphogenesis IMP
IMP: 通过突变表型推断
12050118 MGI
acts upstream of or within intermediate filament organization IGI
IGI: 通过遗传相互作用推断
15601842 MGI
acts upstream of or within keratinization IGI
IGI: 通过遗传相互作用推断
15601842 MGI
acts upstream of or within morphogenesis of an epithelium IGI
IGI: 通过遗传相互作用推断
15601842 MGI
involved in positive regulation of cell growth IMP
IMP: 通过突变表型推断
16710422 MGI
involved in positive regulation of hair follicle development IMP
IMP: 通过突变表型推断
16702408 MGI
involved in positive regulation of translation IMP
IMP: 通过突变表型推断
16710422 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell periphery IDA
IDA: 通过直接分析推断
16682203 MGI
is active in cornified envelope IDA
IDA: 通过直接分析推断
26644517 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
16702408 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

keratin, type I cytoskeletal 17

CK-17

cytokeratin-17

keratin complex 1, acidic, gene 17

Krt17 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Krt17 Q9QWL7 Sfn Mus musculus O70456
IF
16710422
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Krt17 NCBI NCBI:3872