2. Gene
  3. Lhx1 - LIM homeobox protein 1 Gene

Lhx1 - LIM homeobox protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Lim1

基因 ID: 16869 | 基因类型: protein coding

关于 Lhx1

功能概要

Enables DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; generation of neurons; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including animal organ development; gastrulation; and regionalization. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; embryo mesoderm; genitourinary system; gut; and sensory organ. Orthologous to human LHX1 (LIM homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Lhx1 基因产物(1)

mRNA Protein Name
NM_008498.3 NP_032524.1 LIM/homeobox protein Lhx1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IGI
IGI: 通过遗传相互作用推断
17166926 MGI
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
11291865 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
26494787 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9468533 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in S-shaped body morphogenesis IMP
IMP: 通过突变表型推断
17610272 MGI
acts upstream of or within anatomical structure formation involved in morphogenesis IGI
IGI: 通过遗传相互作用推断
10498685 MGI
acts upstream of or within anatomical structure formation involved in morphogenesis IMP
IMP: 通过突变表型推断
15930111 MGI
acts upstream of or within anatomical structure morphogenesis IMP
IMP: 通过突变表型推断
10328927 MGI
acts upstream of or within anterior/posterior axis specification IGI
IGI: 通过遗传相互作用推断
10529425 MGI
acts upstream of or within anterior/posterior pattern specification IGI
IGI: 通过遗传相互作用推断
10498685 MGI
involved in branching involved in ureteric bud morphogenesis IEP
IEP: 通过表达模式推断
7909549 MGI
acts upstream of or within cell differentiation IMP
IMP: 通过突变表型推断
26494787 MGI
acts upstream of or within cell-cell signaling IGI
IGI: 通过遗传相互作用推断
17664423 MGI
acts upstream of or within cerebellar Purkinje cell differentiation IGI
IGI: 通过遗传相互作用推断
17664423 MGI
acts upstream of or within cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation IGI
IGI: 通过遗传相互作用推断
17664423 MGI
acts upstream of or within cerebellum development IGI
IGI: 通过遗传相互作用推断
17664423 MGI
involved in cervix development IMP
IMP: 通过突变表型推断
14695376 MGI
involved in comma-shaped body morphogenesis IMP
IMP: 通过突变表型推断
17610272 MGI
acts upstream of or within dorsal/ventral pattern formation IGI
IGI: 通过遗传相互作用推断
10498685 MGI
acts upstream of or within ectoderm formation IGI
IGI: 通过遗传相互作用推断
10498685 MGI
acts upstream of or within embryonic pattern specification IGI
IGI: 通过遗传相互作用推断
10529425 MGI
involved in embryonic retina morphogenesis in camera-type eye IMP
IMP: 通过突变表型推断
18094249 MGI
involved in embryonic viscerocranium morphogenesis IMP
IMP: 通过突变表型推断
14695376 MGI
acts upstream of or within endoderm development IMP
IMP: 通过突变表型推断
26494787 MGI
acts upstream of or within endoderm formation IMP
IMP: 通过突变表型推断
15355796 MGI
involved in epithelium development IMP
IMP: 通过突变表型推断
14695376 MGI
acts upstream of or within forebrain regionalization IGI
IGI: 通过遗传相互作用推断
10529425 MGI
acts upstream of or within gastrulation with mouth forming second IMP
IMP: 通过突变表型推断
15355796 MGI
acts upstream of or within head development IGI
IGI: 通过遗传相互作用推断
10529425 MGI
involved in head development IGI
IGI: 通过遗传相互作用推断
15857913 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
15930111 MGI
involved in lateral motor column neuron migration IMP
IMP: 通过突变表型推断
20711475 MGI
acts upstream of mesendoderm development IMP
IMP: 通过突变表型推断
26494787 MGI
involved in mesonephros development IEP
IEP: 通过表达模式推断
7909549 MGI
involved in metanephric S-shaped body morphogenesis IEP
IEP: 通过表达模式推断
7909549 MGI
involved in metanephric renal vesicle morphogenesis IEP
IEP: 通过表达模式推断
7909549 MGI
involved in metanephros development IEP
IEP: 通过表达模式推断
7909549 MGI
involved in motor neuron axon guidance IMP
IMP: 通过突变表型推断
20711475 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17610272 MGI
involved in nephric duct elongation IMP
IMP: 通过突变表型推断
16216236 MGI
involved in nephric duct morphogenesis IMP
IMP: 通过突变表型推断
16216236 MGI
involved in oviduct development IMP
IMP: 通过突变表型推断
14695376 MGI
involved in oviduct epithelium development IMP
IMP: 通过突变表型推断
14695376 MGI
involved in paramesonephric duct development IMP
IMP: 通过突变表型推断
14695376 MGI
acts upstream of or within pattern specification process IGI
IGI: 通过遗传相互作用推断
10498685 MGI
acts upstream of or within pattern specification process IMP
IMP: 通过突变表型推断
15930111 MGI
involved in positive regulation of DNA-templated transcription IGI
IGI: 通过遗传相互作用推断
17166926 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
11291865 MGI
involved in positive regulation of anterior head development IMP
IMP: 通过突变表型推断
14695376 MGI
involved in positive regulation of branching involved in ureteric bud morphogenesis IMP
IMP: 通过突变表型推断
16216236 MGI
involved in positive regulation of embryonic development IMP
IMP: 通过突变表型推断
11291865 MGI
involved in positive regulation of gastrulation IMP
IMP: 通过突变表型推断
11291865 MGI
involved in positive regulation of nephron tubule epithelial cell differentiation IMP
IMP: 通过突变表型推断
16216236 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
17664423 MGI
acts upstream of or within primitive streak formation IMP
IMP: 通过突变表型推断
11291865 MGI
involved in primitive streak formation IMP
IMP: 通过突变表型推断
11291865 MGI
involved in pronephros development IEP
IEP: 通过表达模式推断
7909549 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
10328927 MGI
involved in renal vesicle morphogenesis IMP
IMP: 通过突变表型推断
17610272 MGI
involved in retina development in camera-type eye IEP
IEP: 通过表达模式推断
10741426 MGI
involved in retina layer formation IEP
IEP: 通过表达模式推断
10741426 MGI
involved in retina layer formation IMP
IMP: 通过突变表型推断
18094249 MGI
acts upstream of or within somite rostral/caudal axis specification IMP
IMP: 通过突变表型推断
11291865 MGI
involved in spinal cord association neuron differentiation IGI
IGI: 通过遗传相互作用推断
17166926 MGI
involved in spinal cord development IEP
IEP: 通过表达模式推断
7909549 MGI
involved in telencephalon development IEP
IEP: 通过表达模式推断
7909549 MGI
involved in transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15857913 MGI
acts upstream of or within ureter morphogenesis IGI
IGI: 通过遗传相互作用推断
21731775 MGI
acts upstream of or within ureteric bud development IMP
IMP: 通过突变表型推断
15930111 MGI
acts upstream of or within urogenital system development IMP
IMP: 通过突变表型推断
15930111 MGI
involved in uterine epithelium development IMP
IMP: 通过突变表型推断
14695376 MGI
involved in uterus development IMP
IMP: 通过突变表型推断
14695376 MGI
involved in vagina development IMP
IMP: 通过突变表型推断
14695376 MGI
involved in ventral spinal cord development IEP
IEP: 通过表达模式推断
20711475 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
10482234 MGI
located in nucleus IDA
IDA: 通过直接分析推断
8793615 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
15857913 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
26494787 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

LIM/homeobox protein Lhx1

LIM homeo box protein 1

homeobox protein Lim-1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07631 LHX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21365 Lhx1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27884 Lhx1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lhx1 NCBI NCBI:3975
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