1. Gene
  2. Mycl - v-myc avian myelocytomatosis viral oncogene lung carcinoma derived Gene

Mycl - v-myc avian myelocytomatosis viral oncogene lung carcinoma derived Gene

种属: Mus musculus

同用名: L-myc; Lmyc1; Mycl1; Lmyc-1; bHLHe38

基因 ID: 16918 | 基因类型: protein coding

关于 Mycl

功能概要

This gene encodes a basic helix-loop-helix leucine zipper (bHLHZip) protein that heterodimerizes with another bHLHZip protein to drive transcription of targets important for proliferation, Apoptosis and differentiation. Mice lacking this gene product show marked decrease in T-cell priming during Bacterial and viral infections. In humans, this gene was found to be amplified in small-cell lung cancers. Alternate splicing of this gene results in multiple variants. [provided by RefSeq, Dec 2014]

Mycl 基因产物(2)

mRNA Protein Name
NM_001303121.1 NP_001290050.1 protein L-Myc isoform 2
NM_008506.3 NP_032532.1 protein L-Myc isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10229200 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of inner ear auditory receptor cell differentiation IGI
IGI: 通过遗传相互作用推断
23022312 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein L-Myc

L-myc-1 proto-oncogene protein

lung carcinoma myc related oncogene 1

protein L-Myc-1

v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived

v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mycl NCBI NCBI:4610