2. Gene
  3. Slc8b1 - solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 Gene

Slc8b1 - solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NCLX; NCKX6; Slc24a6

基因 ID: 170756 | 基因类型: protein coding

关于 Slc8b1

功能概要

Enables calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential and protein homodimerization activity. Involved in calcium export from the mitochondrion; mitochondrial calcium ion homeostasis; and regulation of lymphocyte chemotaxis. Acts upstream of or within mitochondrial calcium ion transmembrane transport and sodium ion transmembrane transport. Located in mitochondrion and plasma membrane. Is expressed in forelimb bud. Orthologous to human SLC8B1 (solute carrier family 8 member B1). [provided by Alliance of Genome Resources, Apr 2022]

Slc8b1 基因产物(3)

mRNA Protein Name
NM_001177594.1 NP_001171065.1 mitochondrial sodium/calcium exchanger protein isoform 2 precursor
NM_001177595.1 NP_001171066.1 mitochondrial sodium/calcium exchanger protein isoform 3 precursor
NM_133221.2 NP_573484.2 mitochondrial sodium/calcium exchanger protein isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium:sodium antiporter activity IDA
IDA: 通过直接分析推断
14625281 MGI
enables calcium:sodium antiporter activity IMP
IMP: 通过突变表型推断
28445457 MGI
enables calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential IMP
IMP: 通过突变表型推断
24067497 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
20018762 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium export from the mitochondrion IMP
IMP: 通过突变表型推断
24067497 MGI
acts upstream of or within calcium ion transmembrane transport IDA
IDA: 通过直接分析推断
14625281 MGI
involved in mitochondrial calcium ion homeostasis IDA
IDA: 通过直接分析推断
20018762 MGI
involved in mitochondrial calcium ion homeostasis IMP
IMP: 通过突变表型推断
28445457 MGI
acts upstream of or within mitochondrial calcium ion transmembrane transport IDA
IDA: 通过直接分析推断
20018762 MGI
involved in mitochondrial calcium ion transmembrane transport IMP
IMP: 通过突变表型推断
28445457 MGI
involved in regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
20018762 MGI
involved in regulation of lymphocyte chemotaxis IMP
IMP: 通过突变表型推断
27328625 MGI
acts upstream of or within sodium ion transmembrane transport IDA
IDA: 通过直接分析推断
14625281 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
20018762 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
14625281 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitochondrial sodium/calcium exchanger protein

Na(+)/K(+)/Ca(2+)-exchange protein 6

sodium/calcium exchanger protein, mitochondrial

sodium/potassium/calcium exchanger 6, mitochondrial

solute carrier family 24 (sodium/potassium/calcium exchanger), member 6

solute carrier family 24 member 6

solute

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13340 SLC8B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20598 Slc8b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27106 Slc8b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc8b1 NCBI NCBI:80024
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