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  2. Ccr4 - C-C motif chemokine receptor 4 Gene

Ccr4 - C-C motif chemokine receptor 4 Gene

中文名称:CC 基序趋化因子受体 4

种属: Rattus norvegicus

同用名: Cmkbr4

基因 ID: 171054 | 基因类型: protein coding

关于 Ccr4

Primary_assembly 8: 114,176,974-114,178,056 reverse strand.mRatBN7.2:CM026981.1

This gene has 1 transcript (splice variant), 114 orthologues, 24 paralogues and is associated with 12 phenotypes.

功能概要

预测该基因编码的蛋白可启动 CC 趋化因子结合活性和 CC 趋化因子受体活性。参与多个过程,包括正向趋化性的正向调节;对抗生素的反应;和对细菌的反应。位于神经细胞体中。哮喘和肺纤维化的生物标志物。与人 CCR4(CC 基序趋化因子受体 4)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable C-C chemokine binding activity and C-C Chemokine Receptor activity. Involved in several processes, including positive regulation of positive chemotaxis; response to antibiotic; and response to bacterium. Located in neuronal cell body. Biomarker of asthma and pulmonary fibrosis. Orthologous to human CCR4 (C-C motif Chemokine Receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Ccr4 基因产物(1)

mRNA Protein Name
NM_133532.3 NP_598216.3 C-C chemokine receptor type 4
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of positive chemotaxis IDA
IDA: 通过直接分析推断
12651599 RGD
involved in response to bacterium IEP
IEP: 通过表达模式推断
14727120 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuronal cell body IDA
IDA: 通过直接分析推断
11438578 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

C-C chemokine receptor type 4

C-C chemokine receptor 4

chemokine (C-C motif) receptor 4

chemokine (C-C) receptor 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccr4 NCBI NCBI:1233