2. Gene
  3. Maf - avian musculoaponeurotic fibrosarcoma oncogene homolog Gene

Maf - avian musculoaponeurotic fibrosarcoma oncogene homolog Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: c-maf; 2810401A20Rik; A230108G15Rik

基因 ID: 17132 | 基因类型: protein coding

关于 Maf

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within several processes, including regulation of chondrocyte differentiation; regulation of transcription by RNA polymerase II; and sensory organ development. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and lower leg. Used to study cataract 21 multiple types and multiple myeloma. Human ortholog(s) of this gene implicated in Ayme-Gripp syndrome; cataract; and cataract 21 multiple types. Orthologous to human MAF (MAF bZIP transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Maf 基因产物(1)

mRNA Protein Name
NM_001025577.2 NP_001020748.2 transcription factor Maf
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12381733 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
19414009 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12835653 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12381733 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
10603348 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell development IMP
IMP: 通过突变表型推断
10603348 MGI
acts upstream of or within cytokine production IDA
IDA: 通过直接分析推断
15790681 MGI
acts upstream of or within inner ear development IDA
IDA: 通过直接分析推断
21795542 MGI
acts upstream of or within lens development in camera-type eye IMP
IMP: 通过突变表型推断
10383433 MGI
acts upstream of or within lens fiber cell differentiation IMP
IMP: 通过突变表型推断
10383433 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19623612 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
21460847 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12381733 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
10603348 MGI
acts upstream of or within regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
10403649 MGI
acts upstream of or within regulation of chondrocyte differentiation IMP
IMP: 通过突变表型推断
14512017 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15249232 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15249232 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor Maf

V-maf musculoaponeurotic fibrosarcoma oncogene homolog

avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog

c-Maf long form

proto-oncogene c-maf

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-119271 CMLD010509 99.11% 否
HY-RS07956 MAF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07957 MAF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-119271A (-)-CMLD010509 / 否
HY-RS17799 Maf Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24267 Maf Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27194 Mmd Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99136 Anti-Mouse IFN gamma Antibody (H22) Inhibitor 95.00% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Maf NCBI NCBI:4094
Macaca fascicularis Maf NCBI NCBI:102120730
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