1. Gene
  2. Nprl3 - nitrogen permease regulator-like 3 Gene

Nprl3 - nitrogen permease regulator-like 3 Gene

种属: Mus musculus

同用名: Aag; Phg; Mare; HS-26; HS-40; Prox1; CGTHBA; m(alpha)RE

基因 ID: 17168 | 基因类型: protein coding

关于 Nprl3

功能概要

Predicted to contribute to GTPase activator activity. Acts upstream of or within circulatory system development and roof of mouth development. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR1 complex. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human NPRL3 (NPR3 like, GATOR1 complex subunit). [provided by Alliance of Genome Resources, Apr 2022]

Nprl3 基因产物(3)

mRNA Protein Name
NM_001284359.1 NP_001271288.1 GATOR complex protein NPRL3 isoform 1
NM_001284360.1 NP_001271289.1 GATOR complex protein NPRL3 isoform 3
NM_181569.3 NP_853547.1 GATOR complex protein NPRL3 isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aorta morphogenesis IMP
IMP: 通过突变表型推断
22538705 MGI
acts upstream of or within cardiac muscle tissue development IMP
IMP: 通过突变表型推断
22538705 MGI
acts upstream of or within roof of mouth development IMP
IMP: 通过突变表型推断
22538705 MGI
acts upstream of or within ventricular septum development IMP
IMP: 通过突变表型推断
22538705 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

GATOR complex protein NPRL3

-14

alpha globin regulatory element containing

alpha-globin regulatory element-containing gene protein

nitrogen permease regulator 3-like protein

proximal locus to the hemoglobin alpha chain complex

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nprl3 NCBI NCBI:8131