1. Gene
  2. Mbl2 - mannose-binding lectin (protein C) 2 Gene

Mbl2 - mannose-binding lectin (protein C) 2 Gene

种属: Mus musculus

同用名: MBL; L-MBP; MBL-C; MBP-C; RARF/P28A

基因 ID: 17195 | 基因类型: protein coding

关于 Mbl2

功能概要

Predicted to enable several functions, including calcium-dependent protein binding activity; identical protein binding activity; and mannose binding activity. Acts upstream of or within defense response to Other organism and positive regulation of phagocytosis. Located in extracellular space. Is expressed in embryo. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); Bacterial infectious disease (multiple); Fungal infectious disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MBL2 (mannose binding lectin 2). [provided by Alliance of Genome Resources, Apr 2022]

Mbl2 基因产物(2)

mRNA Protein Name
NM_001365058.1 NP_001351987.1 mannose-binding protein C precursor
NM_010776.2 NP_034906.1 mannose-binding protein C precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within complement activation, lectin pathway IDA
IDA: 通过直接分析推断
15148336 MGI
acts upstream of or within complement activation, lectin pathway IGI
IGI: 通过遗传相互作用推断
15148336 MGI
acts upstream of or within complement activation, lectin pathway IMP
IMP: 通过突变表型推断
15148336 MGI
acts upstream of or within defense response to Gram-positive bacterium IGI
IGI: 通过遗传相互作用推断
15148336 MGI
acts upstream of or within killing by host of symbiont cells IGI
IGI: 通过遗传相互作用推断
15148336 MGI
acts upstream of or within positive regulation of phagocytosis IGI
IGI: 通过遗传相互作用推断
15148336 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
15148336 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

mannose-binding protein C

RA-reactive factor P28A subunit

mannan-binding protein

mannose binding lectin, liver (C)

重组 Mbl2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70674 MBL2/COLEC1 Protein, Mouse (HEK293) Q3UEK1 (E19-D244) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mbl2 NCBI NCBI:4153