1. Gene
  2. Mcf2l - mcf.2 transforming sequence-like Gene

Mcf2l - mcf.2 transforming sequence-like Gene

种属: Mus musculus

同用名: Dbs; Ost; mKIAA0362; C130040G20Rik

基因 ID: 17207 | 基因类型: protein coding

关于 Mcf2l

功能概要

Enables 1-phosphatidylinositol binding activity and guanyl-nucleotide exchange factor activity. Acts upstream of or within Rho protein signal transduction and positive regulation of transcription by RNA polymerase II. Located in lamellipodium and membrane. Is expressed in nervous system and retina. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like). [provided by Alliance of Genome Resources, Apr 2022]

Mcf2l 基因产物(11)

mRNA Protein Name
NM_001159485.2 NP_001152957.1 guanine nucleotide exchange factor DBS isoform 3
NM_001159486.2 NP_001152958.1 guanine nucleotide exchange factor DBS isoform 2
NM_001371043.1 NP_001357972.1 guanine nucleotide exchange factor DBS isoform 4
NM_001371044.1 NP_001357973.1 guanine nucleotide exchange factor DBS isoform 5
NM_001371045.1 NP_001357974.1 guanine nucleotide exchange factor DBS isoform 6 precursor
NM_001371046.1 NP_001357975.1 guanine nucleotide exchange factor DBS isoform 7
NM_001371047.1 NP_001357976.1 guanine nucleotide exchange factor DBS isoform 8
NM_001371048.1 NP_001357977.1 guanine nucleotide exchange factor DBS isoform 9 precursor
NM_001371049.1 NP_001357978.1 guanine nucleotide exchange factor DBS isoform 10
NM_001371050.1 NP_001357979.1 guanine nucleotide exchange factor DBS isoform 11
NM_178076.4 NP_835177.2 guanine nucleotide exchange factor DBS isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 1-phosphatidylinositol binding IDA
IDA: 通过直接分析推断
12637522 MGI
enables guanyl-nucleotide exchange factor activity IDA
IDA: 通过直接分析推断
12637522 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11889037 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Rho protein signal transduction IDA
IDA: 通过直接分析推断
12637522 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
17000758 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in lamellipodium IDA
IDA: 通过直接分析推断
12637522 MGI
located in membrane IDA
IDA: 通过直接分析推断
12637522 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

guanine nucleotide exchange factor DBS

DBL's big sister

MCF2-transforming sequence-like protein

Ost gamma

exchange factor for RhoA and Cdc42

guanine nucleotide exchange factor OSTIII

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mcf2l NCBI NCBI:23263