2. Gene
  3. Mtf2 - metal response element binding transcription factor 2 Gene

Mtf2 - metal response element binding transcription factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: M96; Pcl2; 9230112N11Rik

基因 ID: 17765 | 基因类型: protein coding

关于 Mtf2

功能概要

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and methylated histone binding activity. Involved in several processes, including regulation of histone H3-K27 methylation; regulation of transcription by RNA polymerase II; and segment specification. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Part of ESC/E(Z) complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human MTF2 (metal response element binding transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Mtf2 基因产物(7)

mRNA Protein Name
NM_001253877.1 NP_001240806.1 metal-response element-binding transcription factor 2 isoform 2
NM_001253878.1 NP_001240807.1 metal-response element-binding transcription factor 2 isoform 2
NM_001253879.1 NP_001240808.1 metal-response element-binding transcription factor 2 isoform 2
NM_001253880.1 NP_001240809.1 metal-response element-binding transcription factor 2 isoform 2
NM_001359088.1 NP_001346017.1 metal-response element-binding transcription factor 2 isoform 3
NM_001359089.1 NP_001346018.1 metal-response element-binding transcription factor 2 isoform 2
NM_013827.3 NP_038855.2 metal-response element-binding transcription factor 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
7772254 MGI
enables methylated histone binding IDA
IDA: 通过直接分析推断
23104054 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20064376 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in epigenetic regulation of gene expression IMP
IMP: 通过突变表型推断
20144788 MGI
involved in segment specification IMP
IMP: 通过突变表型推断
21059868 MGI
involved in stem cell differentiation IMP
IMP: 通过突变表型推断
20144788 MGI
involved in stem cell population maintenance IMP
IMP: 通过突变表型推断
20144788 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ESC/E(Z) complex IDA
IDA: 通过直接分析推断
20144788 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

metal-response element-binding transcription factor 2

mPCl2

metal regulatory transcription factor 2

metal response element DNA-binding protein M96

polycomb-like protein 2

ziRF1

zinc-regulated factor 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08766 MTF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22243 Mtf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28765 Mtf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mtf2 NCBI NCBI:22823
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