2. Gene
  3. Myt1 - myelin transcription factor 1 Gene

Myt1 - myelin transcription factor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Nzf2; Nzf2a; Nzf2b; Nztf2

基因 ID: 17932 | 基因类型: protein coding

关于 Myt1

功能概要

This gene is a member of the myelin transcription factor 1 gene family. The encoded protein, a zinc finger DNA-binding protein, is involved in regulation of oligodendrocyte differentiation and proliferation in the developing central nervous system. The gene product has a role in remyelination through regeneration of oligodendrocyte lineage cells in response to demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

Myt1 基因产物(4)

mRNA Protein Name
NM_001171615.1 NP_001165086.1 myelin transcription factor 1 isoform 3
NM_001171616.1 NP_001165087.1 myelin transcription factor 1 isoform 2
NM_001171680.1 NP_001165151.1 myelin transcription factor 1 isoform 4
NM_008665.4 NP_032691.2 myelin transcription factor 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
17442045 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17442045 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17442045 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15935060 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within diaphragm development IMP
IMP: 通过突变表型推断
17928203 MGI
acts upstream of or within endocrine pancreas development IMP
IMP: 通过突变表型推断
17928203 MGI
acts upstream of or within intracellular glucose homeostasis IMP
IMP: 通过突变表型推断
17928203 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: 通过突变表型推断
17928203 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: 通过突变表型推断
17928203 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17442045 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
17928203 MGI
acts upstream of or within regulation of hormone metabolic process IMP
IMP: 通过突变表型推断
17928203 MGI
acts upstream of or within regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
17928203 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9373037 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

myelin transcription factor 1

NZF-2

neural zinc finger factor 2

neural zinc finger transcription factor 2

相关产品

Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13925 PD0166285 99.46% 否
HY-122113 PD173952 99.44% 否
HY-145817 (Rac)-lunresertib Inhibitor 99.72% 否
HY-145664 Myt1-IN-1 Inhibitor 98.97% 否
HY-145817B (R)-lunresertib Inhibitor 99.87% 否
HY-145666 Myt1-IN-3 Inhibitor 99.14% 否
HY-145665 Myt1-IN-2 Inhibitor / 否
HY-13925A PD0166285 dihydrochloride / 否
HY-157443 Myt1-IN-4 Inhibitor / 否
HY-RS08973 MYT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08974 MYT1L Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS10605 PKMYT1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-162988 Myt1-IN-5 Inhibitor / 否
HY-RS16738 Pkmyt1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19620 Myt1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21661 Myt1l Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26115 Myt1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Myt1 NCBI NCBI:4661
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