1. Gene
  2. Npr1 - natriuretic peptide receptor 1 Gene

Npr1 - natriuretic peptide receptor 1 Gene

种属: Mus musculus

同用名: GC-A; NPRA; Pndr; NPR-A

基因 ID: 18160 | 基因类型: protein coding

关于 Npr1

功能概要

Enables Guanylate Cyclase activity. Predicted to be involved in several processes, including cGMP biosynthetic process; positive regulation of cGMP-mediated signaling; and receptor guanylyl cyclase signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; limb; and respiratory system. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human NPR1 (natriuretic peptide receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Npr1 基因产物(1)

mRNA Protein Name
NM_008727.5 NP_032753.5 atrial natriuretic peptide receptor 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables guanylate cyclase activity IDA
IDA: 通过直接分析推断
11997476 MGI
enables guanylate cyclase activity IMP
IMP: 通过突变表型推断
11997476 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of blood pressure IDA
IDA: 通过直接分析推断
12727932 MGI
NOT acts upstream of or within regulation of blood pressure IMP
IMP: 通过突变表型推断
11997476 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

atrial natriuretic peptide receptor 1

ANP-A

ANPR-A

Nppa receptor

atrial natriuretic peptide receptor type A

guanylate cyclase A

guanylyl cyclase-A

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Npr1 NCBI NCBI:4881
Macaca fascicularis Npr1 NCBI NCBI:102143449
Rattus norvegicus Npr1 NCBI NCBI:24603