2. Peptides
  3. AP 811 acetate

AP 811 acetate 是一种选择性心房钠尿肽清除受体 (ANP-CR、NPR3) 拮抗剂，Ki 为 0.48 nM。AP 811 acetate 对 NPR3 的选择性比 NPR1 高 20000 倍。AP 811 acetate 消除了 ANP 引起的泵刺激。

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AP 811 acetate Chemical Structure

AP 811 acetate Chemical Structure

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AP 811 acetate 的其他形式现货产品:

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Other Forms of AP 811 acetate:

AP 811 acetate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AP 811 acetate is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a Ki of 0.48 nM. AP 811 acetate displays >20000-fold selectivity for NPR3 over NPR1. AP 811 acetate abolishes ANP-induced pump stimulation[1][2].

IC50 & Target

Ki: 0.48 nM (NPR3)[1]
体外研究
(In Vitro)

在增殖的心肌细胞中，AP 811 acetate (10-500 nM) 可以完全消除低浓度 ANP (10 nM) 所见的增强的心肌细胞增殖[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AP 811 acetate 相关抗体:
Formula

C46H66N12O8.xC2H4O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AP 811AP811AP-811OtherspumpstimulationatrialnatriureticpeptidecardiovasculardiseasesInhibitorinhibitorinhibit

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产品名称：
AP 811 acetate
目录号：
HY-P1419A
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