2. Gene
  3. Ntn1 - netrin 1 Gene

Ntn1 - netrin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Netrin-1

基因 ID: 18208 | 基因类型: protein coding

关于 Ntn1

功能概要

Predicted to be an extracellular matrix structural constituent. Involved in chemorepulsion of axon and regulation of synapse assembly. Acts upstream of or within several processes, including animal organ morphogenesis; generation of neurons; and nuclear migration. Located in basement membrane and cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; integumental system; lung; and sensory organ. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Orthologous to human NTN1 (netrin 1). [provided by Alliance of Genome Resources, Apr 2022]

Ntn1 基因产物(1)

mRNA Protein Name
NM_008744.2 NP_032770.2 netrin-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18585357 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within anterior/posterior axon guidance IMP
IMP: 通过突变表型推断
18479186 MGI
acts upstream of or within axon guidance IDA
IDA: 通过直接分析推断
12051827 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
10908620 MGI
acts upstream of or within axonogenesis IDA
IDA: 通过直接分析推断
10908620 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
16481423 MGI
acts upstream of or within cell-cell adhesion IGI
IGI: 通过遗传相互作用推断
16439476 MGI
involved in chemorepulsion of axon IDA
IDA: 通过直接分析推断
28483977 MGI
acts upstream of glial cell proliferation IMP
IMP: 通过突变表型推断
16481423 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: 通过突变表型推断
17616930 MGI
acts upstream of or within mammary gland development IGI
IGI: 通过遗传相互作用推断
18425773 MGI
acts upstream of or within mammary gland duct morphogenesis IGI
IGI: 通过遗传相互作用推断
16439476 MGI
acts upstream of or within motor neuron migration IMP
IMP: 通过突变表型推断
16267219 MGI
acts upstream of or within negative regulation of axon extension IDA
IDA: 通过直接分析推断
10704383 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
14750959 MGI
acts upstream of or within nuclear migration IDA
IDA: 通过直接分析推断
12051827 MGI
acts upstream of or within positive regulation of axon extension IDA
IDA: 通过直接分析推断
10704383 MGI
acts upstream of or within positive regulation of glial cell proliferation IMP
IMP: 通过突变表型推断
16481423 MGI
acts upstream of or within regulation of cell migration IDA
IDA: 通过直接分析推断
10704383 MGI
acts upstream of or within regulation of glial cell migration IMP
IMP: 通过突变表型推断
16481423 MGI
involved in regulation of synapse assembly EXP
EXP: 通过实验结果推断
24174661 MGI
involved in regulation of synapse assembly IDA
IDA: 通过直接分析推断
24174661 MGI
involved in regulation of synapse assembly IMP
IMP: 通过突变表型推断
24174661 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
18757743 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
18425773 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
24174661 MGI
is active in synapse IDA
IDA: 通过直接分析推断
24174661 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

netrin-1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09621 NTN1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18629 Ntn1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25115 Ntn1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ntn1 NCBI NCBI:9423
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