2. Gene
  3. P4ha2 - procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide Gene

P4ha2 - procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: P4hl

基因 ID: 18452 | 基因类型: protein coding

关于 P4ha2

功能概要

Enables procollagen-proline 4-dioxygenase activity. Acts upstream of or within peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Part of procollagen-proline 4-dioxygenase complex. Is expressed in alimentary system; pectoral girdle and thoracic body wall musculature; and skeleton. Human ortholog(s) of this gene implicated in myopia. Orthologous to human P4HA2 (prolyl 4-hydroxylase subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

P4ha2 基因产物(2)

mRNA Protein Name
NM_001136076.2 NP_001129548.1 prolyl 4-hydroxylase subunit alpha-2 isoform 1 precursor
NM_011031.2 NP_035161.2 prolyl 4-hydroxylase subunit alpha-2 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables procollagen-proline 4-dioxygenase activity IDA
IDA: 通过直接分析推断
7753822 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7753822 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within peptidyl-proline hydroxylation to 4-hydroxy-L-proline IDA
IDA: 通过直接分析推断
7753822 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of procollagen-proline 4-dioxygenase complex IDA
IDA: 通过直接分析推断
7753822 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prolyl 4-hydroxylase subunit alpha-2

4-PH alpha-2

Prolyl 4-hydroxylase alpha IIa subunit

procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-121172 1,4-DPCA Inhibitor 98.36% 否
HY-N2589 Isosaponarin 99.59% 否
HY-RS09943 P4HA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18674 P4ha2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25160 P4ha2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P4ha2 NCBI NCBI:8974
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