2. Gene
  3. Pde3b - phosphodiesterase 3B, cGMP-inhibited Gene

Pde3b - phosphodiesterase 3B, cGMP-inhibited Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 9830102A01Rik

基因 ID: 18576 | 基因类型: protein coding

关于 Pde3b

功能概要

Enables protein kinase B binding activity. Acts upstream of or within several processes, including cellular response to Insulin stimulus; glucose homeostasis; and regulation of Insulin secretion. Located in Golgi apparatus; endoplasmic reticulum; and membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human PDE3B (phosphodiesterase 3B). [provided by Alliance of Genome Resources, Apr 2022]

Pde3b 基因产物(1)

mRNA Protein Name
NM_011055.2 NP_035185.2 cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3',5'-cyclic-AMP phosphodiesterase activity IDA
IDA: 通过直接分析推断
10454575 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
29768196 MGI
enables protein kinase B binding IPI
IPI: 通过物理相互作用推断
10454575 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
10454575 MGI
acts upstream of or within endocrine pancreas development IDA
IDA: 通过直接分析推断
14736883 MGI
acts upstream of or within glucose homeostasis IDA
IDA: 通过直接分析推断
14736883 MGI
acts upstream of or within regulation of insulin secretion IDA
IDA: 通过直接分析推断
14736883 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
10952971 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
10952971 MGI
located in membrane IDA
IDA: 通过直接分析推断
10454575 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

cGMP-inhibited 3',5'-cyclic phosphodiesterase B

CGI-PDE B

CGIPDE1

cyclic GMP-inhibited phosphodiesterase B

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-U00186 K134 Inhibitor 99.84% Phase 2
HY-145924 BAY 2666605 Inhibitor 99.74% Phase 1
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101312 Cilostamide Inhibitor 99.64% 否
HY-136350 BRD9500 Modulator 99.46% 否
HY-136350B (S)-BRD9500 Control 99.67% 否
HY-163285 PDE3B-IN-1 Inhibitor / 否
HY-168966 PDE2 inhibitor 6 / 否
HY-RS10219 PDE3B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18399 Pde3b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24880 Pde3b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pde3b NCBI NCBI:5140
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