2. Gene
  3. Nme1 - NME/NM23 nucleoside diphosphate kinase 1 Gene

Nme1 - NME/NM23 nucleoside diphosphate kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 191575 | 基因类型: protein coding

关于 Nme1

功能概要

Enables several functions, including DNA binding activity; gamma-tubulin binding activity; and nucleoside diphosphate kinase activity. Involved in several processes, including cellular response to glucose stimulus; response to cAMP; and response to testosterone. Located in several cellular components, including centrosome; mitochondrial outer membrane; and perinuclear region of cytoplasm. Colocalizes with intermediate filament. Human ortholog(s) of this gene implicated in neuroblastoma; ovary epithelial cancer; and teratoma. Orthologous to human NME1 (NME/NM23 nucleoside diphosphate kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nme1 基因产物(1)

mRNA Protein Name
NM_138548.2 NP_612557.1 nucleoside diphosphate kinase A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12010125 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
17572440 RGD
enables gamma-tubulin binding IDA
IDA: 通过直接分析推断
11139339 RGD
enables intermediate filament binding IPI
IPI: 通过物理相互作用推断
11082283 RGD
enables nucleoside diphosphate kinase activity IDA
IDA: 通过直接分析推断
11139339 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11302744 RGD
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
12010125 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in GTP biosynthetic process IDA
IDA: 通过直接分析推断
11139339 RGD
involved in cellular response to fatty acid IEP
IEP: 通过表达模式推断
19367376 RGD
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
19367376 RGD
involved in cellular response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11082283 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
18493952 RGD
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
12010125 RGD
involved in negative regulation of myeloid leukocyte differentiation IDA
IDA: 通过直接分析推断
7737424 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
10069391 RGD
involved in response to amine IEP
IEP: 通过表达模式推断
19639176 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
11082283 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
19639176 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11082283 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IDA
IDA: 通过直接分析推断
11139339 RGD
located in intermediate filament IDA
IDA: 通过直接分析推断
11082283 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
22817458 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11082283 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nucleoside diphosphate kinase A

NDK A

NDP kinase A

NDP kinase beta

expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase)

metastasis inhibition factor NM23

non-metastatic cells 1, protein (NM23A) expressed in

nucloside diphosphate kinase

tumor metast

Nme1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Nme1 Q05982 MEN1 Homo sapiens O00255-2
Y2H
11302744
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09371 NME1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09372 NME1-NME2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20309 Nme1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26817 Nme1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nme1 NCBI NCBI:4830
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