1. Gene
  2. Ccl3 - chemokine (C-C motif) ligand 3 Gene

Ccl3 - chemokine (C-C motif) ligand 3 Gene

种属: Mus musculus

同用名: Mip1a; Scya3; G0S19-1; MIP1-(a); LD78alpha; MIP-1alpha; MIP1-alpha

基因 ID: 20302 | 基因类型: protein coding

关于 Ccl3

功能概要

Enables chemokine activity. Involved in several processes, including astrocyte cell migration; macrophage chemotaxis; and positive regulation of macromolecule metabolic process. Located in extracellular space. Is expressed in articular cartilage; cartilage; knee joint; lung; and radius. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL3 (C-C motif chemokine ligand 3). [provided by Alliance of Genome Resources, Apr 2022]

Ccl3 基因产物(1)

mRNA Protein Name
NM_011337.2 NP_035467.1 C-C motif chemokine 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemokine activity IDA
IDA: 通过直接分析推断
7594543 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7594543 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in astrocyte cell migration IDA
IDA: 通过直接分析推断
15155903 MGI
involved in macrophage chemotaxis IGI
IGI: 通过遗传相互作用推断
21784977 MGI
involved in positive regulation of inflammatory response IGI
IGI: 通过遗传相互作用推断
21784977 MGI
involved in positive regulation of interleukin-1 beta production IGI
IGI: 通过遗传相互作用推断
21784977 MGI
involved in positive regulation of neuron apoptotic process IGI
IGI: 通过遗传相互作用推断
15155903 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
15155903 MGI
involved in positive regulation of tumor necrosis factor production IGI
IGI: 通过遗传相互作用推断
21784977 MGI
involved in regulation of cell shape IDA
IDA: 通过直接分析推断
15155903 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
19139201 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

C-C motif chemokine 3

L2G25B

MIP-1-alpha

MIP1 (a)

SIS-alpha

TY-5

heparin-binding chemotaxis protein

macrophage inflammatory protein 1-alpha

macrophage inflammatory protein-1alpha

small-inducible cytokine A3

重组 Ccl3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7255 MIP-1 alpha/CCL3 Protein, Mouse (HEK293) P10855 (A24-A92) ≥95%
HY-P7768 MIP-1 alpha/CCL3 Protein, Mouse (His) P10855/Q5SVU3 (A24-A92) ≥95%
HY-P7768AF Animal-Free MIP-1 alpha/CCL3 Protein, Mouse (His) P10855 (A24-A92) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccl3 NCBI NCBI:6348
Rattus norvegicus Ccl3 NCBI NCBI:25542