1. Gene
  2. Sel1l - sel-1 suppressor of lin-12-like (C. elegans) Gene

Sel1l - sel-1 suppressor of lin-12-like (C. elegans) Gene

种属: Mus musculus

同用名: Sel1h; mKIAA4137

基因 ID: 20338 | 基因类型: protein coding

关于 Sel1l

功能概要

Predicted to contribute to ubiquitin-protein transferase activity. Involved in ERAD pathway; protein secretion; and triglyceride metabolic process. Acts upstream of or within response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum. Predicted to be part of Derlin-1 retrotranslocation complex and Hrd1p ubiquitin Ligase ERAD-L complex. Is expressed in several structures, including genitourinary system; liver; neural tube; pancreas; and spleen. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Sel1l 基因产物(2)

mRNA Protein Name
NM_001039089.1 NP_001034178.1 protein sel-1 homolog 1 isoform a precursor
NM_011344.2 NP_035474.1 protein sel-1 homolog 1 isoform b precursor
蛋白主名 其他名称

protein sel-1 homolog 1

Sel1 (suppressor of lin-12) 1 homolog

sel-1L

suppressor of lin-12-like protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sel1l NCBI NCBI:6400