2. Gene
  3. Sema3f - sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F Gene

Sema3f - sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sema4; Semak

基因 ID: 20350 | 基因类型: protein coding

关于 Sema3f

功能概要

Enables chemorepellent activity. Involved in nervous system development; regulation of postsynapse organization; and ventral trunk neural crest cell migration. Acts upstream of or within generation of neurons; negative chemotaxis; and neural crest cell migration. Located in extracellular space. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human SEMA3F (semaphorin 3F). [provided by Alliance of Genome Resources, Apr 2022]

Sema3f 基因产物(6)

mRNA Protein Name
NM_001311151.3 NP_001298080.1 semaphorin-3F isoform 1 precursor
NM_001379496.2 NP_001366425.1 semaphorin-3F isoform 2 precursor
NM_001405023.1 NP_001391952.1 semaphorin-3F isoform 4 precursor
NM_001405024.1 NP_001391953.1 semaphorin-3F isoform 5 precursor
NM_001405025.2 NP_001391954.1 semaphorin-3F isoform 1 precursor
NM_011349.4 NP_035479.2 semaphorin-3F isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemorepellent activity IDA
IDA: 通过直接分析推断
11683995 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of axon extension involved in axon guidance IDA
IDA: 通过直接分析推断
9753685 MGI
acts upstream of axon extension involved in axon guidance IGI
IGI: 通过遗传相互作用推断
11683995 MGI
involved in axon extension involved in axon guidance IMP
IMP: 通过突变表型推断
22790009 MGI
acts upstream of or within axon guidance IDA
IDA: 通过直接分析推断
12435358 MGI
involved in branchiomotor neuron axon guidance IMP
IMP: 通过突变表型推断
18804103 MGI
involved in facial nerve structural organization IMP
IMP: 通过突变表型推断
18804103 MGI
acts upstream of or within negative chemotaxis IDA
IDA: 通过直接分析推断
16319111 MGI
acts upstream of or within negative chemotaxis IGI
IGI: 通过遗传相互作用推断
11683995 MGI
acts upstream of or within negative regulation of axon extension involved in axon guidance IDA
IDA: 通过直接分析推断
9753685 MGI
acts upstream of or within negative regulation of axon extension involved in axon guidance IGI
IGI: 通过遗传相互作用推断
11683995 MGI
involved in nerve development IMP
IMP: 通过突变表型推断
22790009 MGI
involved in neural crest cell migration involved in autonomic nervous system development IMP
IMP: 通过突变表型推断
19386662 MGI
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
20010807 MGI
involved in regulation of postsynapse organization IMP
IMP: 通过突变表型推断
20010807 MGI
involved in semaphorin-plexin signaling pathway IMP
IMP: 通过突变表型推断
18804103 MGI
involved in sympathetic ganglion development IMP
IMP: 通过突变表型推断
22790009 MGI
involved in sympathetic neuron projection extension IMP
IMP: 通过突变表型推断
22790009 MGI
involved in sympathetic neuron projection guidance IMP
IMP: 通过突变表型推断
22790009 MGI
involved in trigeminal nerve structural organization IMP
IMP: 通过突变表型推断
18804103 MGI
acts upstream of or within trunk neural crest cell migration IMP
IMP: 通过突变表型推断
16319111 MGI
involved in ventral trunk neural crest cell migration IMP
IMP: 通过突变表型推断
19386662 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20010807 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
20010807 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

semaphorin-3F

semaphorin IV

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12655 SEMA3F Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20594 Sema3f Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27102 Sema3f Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sema3f NCBI NCBI:6405
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