2. Gene
  3. Sgpl1 - sphingosine phosphate lyase 1 Gene

Sgpl1 - sphingosine phosphate lyase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Spl; S1PL; D10Xrf456

基因 ID: 20397 | 基因类型: protein coding

关于 Sgpl1

功能概要

Predicted to enable sphinganine-1-phosphate aldolase activity. Acts upstream of or within several processes, including animal organ development; cellular hormone metabolic process; and face morphogenesis. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Orthologous to human SGPL1 (sphingosine-1-phosphate lyase 1). [provided by Alliance of Genome Resources, Apr 2022]

Sgpl1 基因产物(3)

mRNA Protein Name
NM_001316673.1 NP_001303602.1 sphingosine-1-phosphate lyase 1
NM_001316674.1 NP_001303603.1 sphingosine-1-phosphate lyase 1
NM_009163.4 NP_033189.2 sphingosine-1-phosphate lyase 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Leydig cell differentiation IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within androgen metabolic process IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within estrogen metabolic process IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within excretion IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within face morphogenesis IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within female gonad development IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within fibroblast migration IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within hemopoiesis IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within luteinization IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within platelet-derived growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within roof of mouth development IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within vasculogenesis IMP
IMP: 通过突变表型推断
17143286 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
28165339 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sphingosine-1-phosphate lyase 1

SP-lyase 1

SPL 1

sphingosine-1-phosphate aldolase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12809 SGPL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-D2284 SGPL1 fluorogenic substrate / 否
HY-RS21755 Sgpl1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sgpl1 NCBI NCBI:8879
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