2. Gene
  3. Sox1 - SRY (sex determining region Y)-box 1 Gene

Sox1 - SRY (sex determining region Y)-box 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sox-1

基因 ID: 20664 | 基因类型: protein coding

关于 Sox1

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in interneuron migration; regulation of oligodendrocyte differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to leukemia inhibitory factor; generation of neurons; and lens morphogenesis in camera-type eye. Located in nucleus. Is expressed in several structures, including central nervous system; eye; genitourinary system; large intestine; and neural ectoderm. Orthologous to human SOX1 (SRY-box transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sox1 基因产物(1)

mRNA Protein Name
NM_009233.3 NP_033259.2 transcription factor SOX-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
8625802 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
9512512 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
9512512 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15110721 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
9512512 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IDA
IDA: 通过直接分析推断
20439489 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
15882093 MGI
acts upstream of or within forebrain neuron development IMP
IMP: 通过突变表型推断
15882093 MGI
acts upstream of or within forebrain neuron differentiation IMP
IMP: 通过突变表型推断
15882093 MGI
involved in interneuron migration IMP
IMP: 通过突变表型推断
20844123 MGI
acts upstream of or within lens morphogenesis in camera-type eye IMP
IMP: 通过突变表型推断
9512512 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
15110721 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
15882093 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9512512 MGI
involved in regulation of oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
19723505 MGI
acts upstream of or within ventral spinal cord interneuron specification IMP
IMP: 通过突变表型推断
20844123 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9512512 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor SOX-1

SRY-box containing gene 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-133028 CKI-7 free base Inhibitor / 否
HY-RS13582 SOX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W011109 CKI-7 Inhibitor / 否
HY-RS19383 Sox1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25875 Sox1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sox1 NCBI NCBI:6656
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