Pycr1 - pyrroline-5-carboxylate reductase 1 Gene

种属: Mus musculus

同用名: P5CR1; P5CR 1

关于 Pycr1

功能概要

Predicted to enable identical protein binding activity and pyrroline-5-carboxylate reductase activity. Predicted to be involved in several processes, including L-proline biosynthetic process; negative regulation of hydrogen peroxide-induced cell death; and regulation of mitochondrial membrane potential. Predicted to act upstream of or within cellular amino acid biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; ear; genitourinary system; skeleton; and telencephalon. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIB and autosomal recessive cutis laxa type IIIB. Orthologous to human PYCR1 (pyrroline-5-carboxylate reductase 1). [provided by Alliance of Genome Resources, Apr 2022]