1. Gene
  2. Tial1 - Tia1 cytotoxic granule-associated RNA binding protein-like 1 Gene

Tial1 - Tia1 cytotoxic granule-associated RNA binding protein-like 1 Gene

种属: Mus musculus

同用名: TIAR; mTIAR; 5330433G13Rik

基因 ID: 21843 | 基因类型: protein coding

关于 Tial1

功能概要

Enables mRNA 3'-UTR AU-rich region binding activity. Acts upstream of or within germ cell development; positive regulation of cell population proliferation; and stem cell division. Located in cytoplasmic stress granule and nucleus. Is expressed in several structures, including branchial arch; central nervous system; sensory organ; and trunk. Orthologous to human TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1). [provided by Alliance of Genome Resources, Apr 2022]

Tial1 基因产物(3)

mRNA Protein Name
NM_001347640.1 NP_001334569.1 nucleolysin TIAR isoform 2
NM_001347641.1 NP_001334570.1 nucleolysin TIAR isoform 3
NM_009383.2 NP_033409.1 nucleolysin TIAR isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: 通过直接分析推断
10921895 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20477871 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within germ cell development IMP
IMP: 通过突变表型推断
9482885 MGI
acts upstream of or within positive regulation of stem cell proliferation IMP
IMP: 通过突变表型推断
9482885 MGI
acts upstream of or within stem cell division IMP
IMP: 通过突变表型推断
9482885 MGI
acts upstream of stem cell proliferation IMP
IMP: 通过突变表型推断
9482885 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16278295 MGI
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
19825938 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9482885 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

nucleolysin TIAR

TIA-1-related protein

Tial1 cytotoxic granule-associated RNA binding protein-like 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tial1 NCBI NCBI:7073