1. Gene
  2. LRRC55 - leucine rich repeat containing 55 Gene

LRRC55 - leucine rich repeat containing 55 Gene

中文名称:含富含亮氨酸的重复序列 55

种属: Homo sapiens

基因 ID: 219527 | 基因类型: protein coding

关于 LRRC55

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:57,181,953-57,191,717 (from NCBI)

This gene has 2 transcripts (splice variants), 119 orthologues and 25 paralogues. Broad expression in brain (RPKM 2.8), lymph node (RPKM 1.5) and 14 other tissues.

功能概要

启用钾通道激活剂活性;跨膜转运蛋白结合活性;和电压门控钾通道活动。参与电压门控钾通道活性和钾离子跨膜转运的正向调节。电压门控钾通道复合体的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables Potassium Channel activator activity; transmembrane transporter binding activity; and voltage-gated Potassium Channel activity. Involved in positive regulation of voltage-gated Potassium Channel activity and potassium ion transmembrane transport. Part of voltage-gated Potassium Channel complex. [provided by Alliance of Genome Resources, Apr 2022]

LRRC55 基因产物(1)

mRNA Protein Name
NM_001005210.4 NP_001005210.2 leucine-rich repeat-containing protein 55 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables potassium channel activator activity IDA
IDA: 通过直接分析推断
22547800 GOA
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
22547800 GOA
enables voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
22547800 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
22547800 GOA
involved in potassium ion transmembrane transport IDA
IDA: 通过直接分析推断
22547800 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
22547800 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

LRRC55 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (81 - 107)

(111 - 124)

LRR_8

LRR_8: Leucine rich repeat (133 - 190)

  • 0
  • 100
  • 200
  • 300
  • 341 a.a.
蛋白主名 其他名称

leucine-rich repeat-containing protein 55

BK channel auxiliary gamma subunit LRRC55

关联疾病

疾病名称 别名
Lymph Node Carcinoma

Lymph Node Cancer

Lymph Node Neoplasm

Neoplasm Of Lymph Node

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus LRRC55 VGNC VGNC:82022
Macaca mulatta LRRC55 VGNC VGNC:107455
Mus musculus LRRC55 MGD MGI:2685197
Canis familiaris LRRC55 VGNC VGNC:42805
Bos taurus LRRC55 VGNC VGNC:31022
Rattus norvegicus LRRC55 RGD RGD:1561726