KIF6 - kinesin family member 6 Gene

中文名称：驱动蛋白家族成员 6

种属: Homo sapiens

同用名: C6orf102; dJ137F1.4; dJ188D3.1; dJ1043E3.1

关于 KIF6

功能概要

该基因编码分子马达家族的一个成员，该家族参与蛋白质复合物、膜细胞器和信使核糖核酸沿微管的细胞内运输。驱动蛋白作为同源二聚体分子发挥作用，具有两个沿微管移动的 N 末端头部结构域和两个通过衔接分子直接或间接与运输的货物相互作用的 C 末端尾部结构域。该基因在冠状动脉和其他血管组织中普遍表达。该基因中自然发生的突变与冠心病有关。[RefSeq 提供，2017 年 5 月]

This gene encodes a member of a family of molecular motors which are involved in intracellular transport of protein complexes, membrane organelles, and messenger ribonucleic acid along microtubules. Kinesins function as homodimeric molecules with two N-terminal head domains that move along microtubules and two C-terminal tail domains that interact with the transported cargo, either directly or indirectly, through adapter molecules. This gene is ubiquitously expressed in coronary arteries and Other vascular tissue. A naturally occurring mutation in this gene is associated with coronary heart disease. [provided by RefSeq, May 2017]