2. Gene
  3. Eppk1 - epiplakin 1 Gene

Eppk1 - epiplakin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: EPPK; EPIPL; EPIPL1; 6230424I18Rik

基因 ID: 223650 | 基因类型: protein coding

关于 Eppk1

功能概要

Enables keratin filament binding activity. Involved in several processes, including intermediate filament bundle assembly; negative regulation of keratinocyte migration; and regulation of epithelial cell proliferation. Located in several cellular components, including apicolateral plasma membrane; basal part of cell; and cell-cell junction. Colocalizes with keratin filament. Is expressed in several structures, including alimentary system; liver and biliary system; respiratory system; sensory organ; and skin. Orthologous to human EPPK1 (epiplakin 1). [provided by Alliance of Genome Resources, Apr 2022]

Eppk1 基因产物(1)

mRNA Protein Name
NM_144848.2 NP_659097.2 epiplakin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables keratin filament binding IPI
IPI: 通过物理相互作用推断
18285451 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytoskeleton organization IMP
IMP: 通过突变表型推断
23599337 MGI
involved in intermediate filament bundle assembly IMP
IMP: 通过突变表型推断
20926261 MGI
involved in intermediate filament organization IDA
IDA: 通过直接分析推断
25617501 MGI
involved in intermediate filament organization IMP
IMP: 通过突变表型推断
18285451 MGI
involved in negative regulation of keratinocyte migration IMP
IMP: 通过突变表型推断
16382146 MGI
involved in negative regulation of keratinocyte proliferation IMP
IMP: 通过突变表型推断
16382146 MGI
involved in negative regulation of wound healing IMP
IMP: 通过突变表型推断
20926261 MGI
involved in positive regulation of epithelial cell proliferation involved in wound healing IMP
IMP: 通过突变表型推断
23599337 MGI
involved in regulation of epithelial cell differentiation IMP
IMP: 通过突变表型推断
23599337 MGI
involved in regulation of epithelium regeneration IMP
IMP: 通过突变表型推断
16382146 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
25232867 MGI
located in basal part of cell IDA
IDA: 通过直接分析推断
23599337 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
23599337 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
12791695 MGI
located in cytoskeleton IDA
IDA: 通过直接分析推断
25617501 MGI
colocalizes with keratin filament IDA
IDA: 通过直接分析推断
18285451 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

epiplakin

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04450 EPPK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07472 KRT9 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20399 Eppk1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26908 Eppk1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eppk1 NCBI NCBI:83481
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