2. Gene
  3. Otud7b - OTU domain containing 7B Gene

Otud7b - OTU domain containing 7B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Za20d1; CEZANNE; Trabid2; 2900060B22Rik; 4930463P07Rik

基因 ID: 229603 | 基因类型: protein coding

关于 Otud7b

功能概要

Enables K63-linked polyubiquitin modification-dependent protein binding activity and thiol-dependent Deubiquitinase. Involved in several processes, including negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of transcription by RNA polymerase II; and protein K48-linked deubiquitination. Acts upstream of or within in utero embryonic development and protein deubiquitination. Located in cytoplasm. Orthologous to human OTUD7B (OTU Deubiquitinase 7B). [provided by Alliance of Genome Resources, Apr 2022]

Otud7b 基因产物(2)

mRNA Protein Name
NM_001025613.1 NP_001020784.1 OTU domain-containing protein 7B
NM_001025614.1 NP_001020785.1 OTU domain-containing protein 7B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables K63-linked polyubiquitin modification-dependent protein binding IDA
IDA: 通过直接分析推断
18281465 MGI
enables cysteine-type deubiquitinase activity IDA
IDA: 通过直接分析推断
12682062 MGI
enables cysteine-type deubiquitinase activity IMP
IMP: 通过突变表型推断
23334419 MGI
enables cysteine-type peptidase activity IMP
IMP: 通过突变表型推断
23334419 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18281465 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
27996060 MGI
involved in mucosal immune response IMP
IMP: 通过突变表型推断
23334419 MGI
involved in negative regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
23334419 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
21097510 MGI
involved in protein K48-linked deubiquitination IMP
IMP: 通过突变表型推断
23334419 MGI
acts upstream of or within protein deubiquitination IDA
IDA: 通过直接分析推断
12682062 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12682062 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

OTU domain-containing protein 7B

TRAF binding domain containing 2

cellular zinc finger anti-NF-kappa-B protein

zinc finger A20 domain-containing protein 1

zinc finger protein Cezanne

zinc finger, A20 domain containing 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09877 OTUD7B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20186 Otud7b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26690 Otud7b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Otud7b NCBI NCBI:56957
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