2. Gene
  3. IGSF9B - immunoglobulin superfamily member 9B Gene

IGSF9B - immunoglobulin superfamily member 9B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：免疫球蛋白超家族成员 9B

种属: Homo sapiens

同用名: LINC00947; MIR4697HG

基因 ID: 22997 | 基因类型: protein coding

关于 IGSF9B

Cytogenetic location: 11q25 Genomic coordinates (GRCh38): 11:133,896,438-133,956,968 (from NCBI)

This gene has 7 transcripts (splice variants), 270 orthologues and 36 paralogues. Broad expression in brain (RPKM 1.7), testis (RPKM 1.1) and 21 other tissues.

功能概要

预测启用激酶结合活性。预测参与突触膜粘附。预计通过质膜粘附分子和抑制性突触后电位的正调节作用于嗜同细胞粘附的上游或内部。预测位于树突中；抑制性突触；和神经细胞体。预计在 GABA 能突触中活跃；神经元投射；和对称突触的突触后特化。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable kinase binding activity. Predicted to be involved in synaptic membrane adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules and positive regulation of inhibitory postsynaptic potential. Predicted to be located in dendrite; inhibitory synapse; and neuronal cell body. Predicted to be active in GABA-ergic synapse; neuron projection; and postsynaptic specialization of symmetric synapse. [provided by Alliance of Genome Resources, Apr 2022]

IGSF9B 基因产物(1)

mRNA Protein Name
NM_001277285.4 NP_001264214.1 protein turtle homolog B precursor

IGSF9B 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (29 - 131)

I-set

I-set: Immunoglobulin I-set domain (140 - 225)

I-set

I-set: Immunoglobulin I-set domain (230 - 321)

Ig_2

Ig_2: Immunoglobulin domain (328 - 413)

I-set

I-set: Immunoglobulin I-set domain (433 - 505)

fn3

fn3: Fibronectin type III domain (512 - 594)

fn3

fn3: Fibronectin type III domain (622 - 698)

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  • 1349 a.a.
蛋白主名 其他名称

protein turtle homolog B

MIR4697 host gene (non-protein coding)

关联疾病

疾病名称 别名
Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary
Tetralogy Of Fallot

TOF

Fallot Tetralogy

Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle

Tetrad Of Fallot

Fallot Tetrad

Fallot Disease

Fallot Complex

Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy

Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle

Interventricular Septal Defect, In Tetralogy Of Fallot

Ventricular Septal Defect With Obstructed Right Ventricular Outflow

Tof - [Tetralogy Of Fallot]

Pulmonary Atresia With Ventricular Septal Defect [Fallot Type]

Pulmonary Atresia, Ventricular Septal Defect And Mapcas

Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]
Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06653 IGSF9B Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus IGSF9B MGD MGI:2685354
Bos taurus IGSF9B VGNC VGNC:30098
Canis familiaris IGSF9B VGNC VGNC:41920
Rattus norvegicus IGSF9B RGD RGD:1564717
Macaca mulatta IGSF9B VGNC VGNC:101287
Felis catus IGSF9B VGNC VGNC:62898
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