2. Gene
  3. Crocc - ciliary rootlet coiled-coil, rootletin Gene

Crocc - ciliary rootlet coiled-coil, rootletin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 230872 | 基因类型: protein coding

关于 Crocc

功能概要

Enables actin binding activity; Kinesin binding activity; and structural molecule activity. A structural constituent of Cytoskeleton. Acts upstream of or within ciliary basal body organization; establishment of organelle localization; and tissue homeostasis. Located in several cellular components, including cytoskeleton; photoreceptor inner segment; and subapical part of cell. Is expressed in brain; metanephros; and retina layer. Orthologous to human CROCC (ciliary rootlet coiled-coil, rootletin). [provided by Alliance of Genome Resources, Apr 2022]

Crocc 基因产物(2)

mRNA Protein Name
NM_001145958.1 NP_001139430.1 rootletin isoform 2
NM_172122.2 NP_742120.2 rootletin isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
15870283 MGI
enables kinesin binding IPI
IPI: 通过物理相互作用推断
16018997 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
23746204 MGI
enables structural constituent of cytoskeleton IMP
IMP: 通过突变表型推断
15870283 MGI
enables structural molecule activity IDA
IDA: 通过直接分析推断
12427867 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular homeostasis IMP
IMP: 通过突变表型推断
15870283 MGI
acts upstream of or within ciliary basal body organization IMP
IMP: 通过突变表型推断
15870283 MGI
acts upstream of or within epithelial structure maintenance IMP
IMP: 通过突变表型推断
15870283 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
15870283 MGI
acts upstream of or within establishment of organelle localization IMP
IMP: 通过突变表型推断
15870283 MGI
acts upstream of or within photoreceptor cell maintenance IMP
IMP: 通过突变表型推断
15870283 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in 9+2 motile cilium IDA
IDA: 通过直接分析推断
29891944 MGI
located in centriole IDA
IDA: 通过直接分析推断
16339073 MGI
located in ciliary rootlet IDA
IDA: 通过直接分析推断
16018997 MGI
located in ciliary rootlet IMP
IMP: 通过突变表型推断
15870283 MGI
located in photoreceptor inner segment IDA
IDA: 通过直接分析推断
23178122 MGI
located in subapical part of cell IDA
IDA: 通过直接分析推断
29891944 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

rootletin

ciliary rootlet coiled-coil protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03193 CROCC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22457 Crocc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28980 Crocc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Crocc NCBI NCBI:9696
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