1. Gene
  2. Npc1l1 - NPC1 like intracellular cholesterol transporter 1 Gene

Npc1l1 - NPC1 like intracellular cholesterol transporter 1 Gene

种属: Mus musculus

同用名: Gm243; 9130221N23Rik

基因 ID: 237636 | 基因类型: protein coding

关于 Npc1l1

功能概要

Predicted to enable heterocyclic compound binding activity; Myosin V binding activity; and small GTPase binding activity. Acts upstream of or within Cholesterol homeostasis. Predicted to be located in brush border membrane. Predicted to be spanning component of plasma membrane. Orthologous to human NPC1L1 (NPC1 like intracellular Cholesterol transporter 1). [provided by Alliance of Genome Resources, Apr 2022]

Npc1l1 基因产物(1)

mRNA Protein Name
NM_207242.2 NP_997125.2 NPC1-like intracellular cholesterol transporter 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
29880681 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
14976318 MGI
involved in cholesterol transport IMP
IMP: 通过突变表型推断
14976318 MGI
involved in intestinal cholesterol absorption IMP
IMP: 通过突变表型推断
14976318 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

NPC1-like intracellular cholesterol transporter 1

NPC1-like 1

Niemann-Pick disease, type C1

Niemann-Pick disease, type C1-like 1

niemann-Pick C1-like protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Npc1l1 NCBI NCBI:29881