1. Gene
  2. B2m - beta-2 microglobulin Gene

B2m - beta-2 microglobulin Gene

种属: Rattus norvegicus

基因 ID: 24223 | 基因类型: protein coding

关于 B2m

功能概要

Predicted to enable MHC class II protein complex binding activity and protein homodimerization activity. Involved in response to cadmium ion and response to xenobiotic stimulus. Located in extracellular space. Biomarker of acute kidney failure; pyelonephritis; and ureteral obstruction. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; immunodeficiency 43; and inflammatory bowel disease. Orthologous to human B2M (beta-2-microglobulin). [provided by Alliance of Genome Resources, Apr 2022]

B2m 基因产物(1)

mRNA Protein Name
NM_012512.2 NP_036644.1 beta-2-microglobulin precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to cadmium ion IEP
IEP: 通过表达模式推断
17327699 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17211973 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
3516141 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

beta-2-microglobulin

beta-2-microglobulin C-terminal fragment (55 AA)

重组 B2m 蛋白

直系同源

种属 基因名 来源 基因 ID
Homo sapiens B2m NCBI NCBI:567
Macaca fascicularis B2m NCBI NCBI:101867173
Canis lupus familiaris B2m NCBI
Mus musculus B2m NCBI NCBI:12010
Susscrofa domestica B2m NCBI
Leporidae B2m NCBI
Macaca mulatta B2m NCBI NCBI:712428