2. Gene
  3. Gata2 - GATA binding protein 2 Gene

Gata2 - GATA binding protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25159 | 基因类型: protein coding

关于 Gata2

功能概要

Enables sequence-specific DNA binding activity. Involved in several processes, including cochlea development; neuron migration; and regulation of vesicle-mediated transport. Located in nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia; immunodeficiency 21; mental depression; myelodysplastic syndrome; and myeloid leukemia. Orthologous to human GATA2 (GATA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Gata2 基因产物(1)

mRNA Protein Name
NM_033442.1 NP_254277.1 endothelial transcription factor GATA-2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12557015 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11093771 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cochlea development IEP
IEP: 通过表达模式推断
20006695 RGD
involved in neuron migration IMP
IMP: 通过突变表型推断
21430145 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
22390417 RGD
involved in positive regulation of mast cell degranulation IMP
IMP: 通过突变表型推断
22390417 RGD
involved in positive regulation of neuron differentiation IMP
IMP: 通过突变表型推断
21430145 RGD
involved in positive regulation of phagocytosis IDA
IDA: 通过直接分析推断
12933836 RGD
involved in positive regulation of phagocytosis, engulfment IMP
IMP: 通过突变表型推断
12933836 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
11093771 RGD
involved in response to lipid IEP
IEP: 通过表达模式推断
11880336 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

endothelial transcription factor GATA-2

GATA-bindning protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05290 GATA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20027 Gata2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26530 Gata2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gata2 NCBI NCBI:2624
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