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  3. Htr4 - 5-hydroxytryptamine receptor 4 Gene

Htr4 - 5-hydroxytryptamine receptor 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：5-羟色胺受体 4

种属: Rattus norvegicus

基因 ID: 25324 | 基因类型: protein coding

关于 Htr4

Primary_assembly 18: 55,766,725-55,949,321 forward strand.mRatBN7.2:CM026991.1

This gene has 6 transcripts (splice variants), 201 orthologues, 35 paralogues and is associated with 10 phenotypes. Biased expression in Brain (RPKM 13.), Kidney (RPKM 3.6) and 4 other tissues.

功能概要

该基因编码的蛋白可启动 G 蛋白偶联血清素受体活性。参与腺苷酸环化酶激活 G 蛋白偶联受体信号通路和γ-氨基丁酸信号通路。预测位于细胞质和细胞膜。预计在树突中活跃。预计是质膜的组成部分。与人类 HTR4（5-羟色胺受体 4）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled serotonin receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and gamma-aminobutyric acid signaling pathway. Predicted to be located in cytoplasm and membrane. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Orthologous to human HTR4 (5-hydroxytryptamine receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Htr4 基因产物(1)

mRNA Protein Name
NM_012853.2 NP_036985.2 5-hydroxytryptamine receptor 4

Htr4 蛋白结构

7tmA_5-HT4

7tmA_5-HT4: cd15056 (19 - 322)

7tmA_5-HT4

7tmA_5-HT4: cd15056 (20 - 46)

7tmA_5-HT4

7tmA_5-HT4: cd15056 (54 - 80)

7tmA_5-HT4

7tmA_5-HT4: cd15056 (92 - 122)

7tmA_5-HT4

7tmA_5-HT4: cd15056 (135 - 158)

7tmA_5-HT4

7tmA_5-HT4: cd15056 (188 - 217)

7tmA_5-HT4

7tmA_5-HT4: cd15056 (251 - 281)

7tmA_5-HT4

7tmA_5-HT4: cd15056 (290 - 315)

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  • 388 a.a.
蛋白主名 其他名称

5-hydroxytryptamine receptor 4

5 hydroxytryptamine ( serotonin) receptor 4

5-HT-4

5-HT4 receptor (two splicing variants L and S)

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

serotonin receptor 4

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-14153A Tegaserod maleate 99.90% 否
HY-14153 Tegaserod 99.89% 否
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14153S Tegaserod-d11 / 否
HY-RS06474 HTR4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06475 Htr4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06476 Htr4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Htr4 NCBI NCBI:3360
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