1. Gene
  2. Scn2b - sodium voltage-gated channel beta subunit 2 Gene

Scn2b - sodium voltage-gated channel beta subunit 2 Gene

种属: Rattus norvegicus

同用名: SCNB2

基因 ID: 25349 | 基因类型: protein coding

关于 Scn2b

功能概要

Enables voltage-gated Sodium Channel activity. Involved in nervous system development and response to pyrethroid. Predicted to be part of voltage-gated Sodium Channel complex. Predicted to be active in plasma membrane. Used to study visual epilepsy. Biomarker of otitis media. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Orthologous to human SCN2B (sodium voltage-gated channel beta subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Scn2b 基因产物(1)

mRNA Protein Name
NM_012877.2 NP_037009.1 sodium channel subunit beta-2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11238277 RGD
enables sodium channel regulator activity IDA
IDA: 通过直接分析推断
22992729 RGD
enables voltage-gated sodium channel activity IDA
IDA: 通过直接分析推断
8521473 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in nervous system development IEP
IEP: 通过表达模式推断
19269275 RGD
involved in response to pyrethroid IDA
IDA: 通过直接分析推断
19026681 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in axon initial segment IDA
IDA: 通过直接分析推断
22992729 RGD
is active in node of Ranvier IDA
IDA: 通过直接分析推断
22992729 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
22992729 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

sodium channel subunit beta-2

Sodium channel beta 2

sodium channel, voltage-gated, type II, beta polypeptide

sodium channel, voltage-gated, type II, beta subunit

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Scn2b NCBI NCBI:6327