2. Gene
  3. Cd44 - CD44 molecule (Indian blood group) Gene

Cd44 - CD44 molecule (Indian blood group) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CD44A; METAA; RHAMM

基因 ID: 25406 | 基因类型: protein coding

关于 Cd44

功能概要

Enables epidermal growth factor receptor binding activity; phosphoprotein binding activity; and protein kinase binding activity. Involved in several processes, including blood vessel maturation; macrophage fusion; and positive regulation of neutrophil apoptotic process. Located in apical plasma membrane; basolateral plasma membrane; and nucleus. Part of protein-containing complex. Biomarker of borna disease and cholestasis. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate Cancer. Orthologous to human CD44 (CD44 molecule (Indian blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Cd44 基因产物(1)

mRNA Protein Name
NM_012924.3 NP_037056.3 CD44 antigen precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables epidermal growth factor receptor binding IPI
IPI: 通过物理相互作用推断
21349584 RGD
enables phosphoprotein binding IPI
IPI: 通过物理相互作用推断
11316791 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15659388 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
8103744 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in blood vessel maturation IEP
IEP: 通过表达模式推断
15947460 RGD
involved in cell adhesion IMP
IMP: 通过突变表型推断
16306150 RGD
involved in cell migration IMP
IMP: 通过突变表型推断
16306150 RGD
involved in macrophage fusion IMP
IMP: 通过突变表型推断
16195325 RGD
involved in neuron projection development IMP
IMP: 通过突变表型推断
17760872 RGD
involved in positive regulation of neutrophil apoptotic process IMP
IMP: 通过突变表型推断
11044212 RGD
involved in postsynapse organization IDA
IDA: 通过直接分析推断
27798233 RGD
involved in postsynapse organization IMP
IMP: 通过突变表型推断
27798233 RGD
involved in regulation of cell growth IDA
IDA: 通过直接分析推断
11316791 RGD
involved in regulation of modification of postsynaptic structure EXP
EXP: 通过实验结果推断
27798233 RGD
involved in regulation of modification of postsynaptic structure IDA
IDA: 通过直接分析推断
27798233 RGD
involved in regulation of modification of postsynaptic structure IMP
IMP: 通过突变表型推断
27798233 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
31966914 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
17105903 RGD
involved in response to vitamin A IEP
IEP: 通过表达模式推断
16804311 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
16786159 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
16786159 RGD
located in cell surface IDA
IDA: 通过直接分析推断
31723344 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
27798233 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
27798233 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
27798233 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
27798233 RGD
is active in presynapse IDA
IDA: 通过直接分析推断
27798233 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
11316791 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CD44 antigen

Cell surface glycoprotein CD44 (hyaluronate binding protein)

ECMR-III

GP90 lymphocyte homing/adhesion receptor

HUTCH-I

PGP-1

PGP-I

extracellular matrix receptor III

hermes antigen

hyaluronate receptor

phagocytic glycoprotein 1

phagocytic glycopr

相关产品

Pre-clinical Phase
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991559 Anti-CD44 Antibody Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd44 NCBI NCBI:960
Macaca fascicularis Cd44 NCBI NCBI:101867504
Mus musculus Cd44 NCBI NCBI:12505
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