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  2. SEC31B - SEC31 homolog B, COPII coat complex component Gene

SEC31B - SEC31 homolog B, COPII coat complex component Gene

中文名称:SEC31 同系物 B,COPII 涂层复杂成分

种属: Homo sapiens

同用名: SEC31L2; SEC31B-1

基因 ID: 25956 | 基因类型: protein coding

关于 SEC31B

Cytogenetic location: 10q24.31 Genomic coordinates (GRCh38): 10:100,486,647-100,519,861 (from NCBI)

This gene has 13 transcripts (splice variants), 195 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 7.5), lymph node (RPKM 6.5) and 24 other tissues.

功能概要

该基因编码一种功能未知的蛋白质。该蛋白与大鼠 VAP1 蛋白具有适度的相似性,后者是一种内体膜相关蛋白,含有假定的 Ca2+/钙调蛋白依赖性激酶 II 磷酸化位点。[RefSeq 提供,2008 年 7 月]

This gene encodes a protein of unknown function. The protein has moderate similarity to rat VAP1 protein which is an endosomal membrane-associated protein, containing a putative Ca2+/calmodulin-dependent kinase II phosphorylation site. [provided by RefSeq, Jul 2008]

SEC31B 基因产物(1)

mRNA Protein Name
NM_015490.4 NP_056305.1 protein transport protein Sec31B
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of vesicle coat IDA
IDA: 通过直接分析推断
22792322 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SEC31B 蛋白结构

WD40

WD40: WD domain, G-beta repeat (119 - 150)

WD40

WD40: WD domain, G-beta repeat (251 - 285)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1179 a.a.
蛋白主名 其他名称

protein transport protein Sec31B

SEC31 homolog B, COPII coating complex component

关联疾病

疾病名称 别名
Retinitis Pigmentosa 47

RP47

Retinitis Pigmentosa, Type 47

Retinitis Pigmentosa 37

RP37

Retinitis Pigmentosa-37

Retinitis Pigmentosa, Type 37

Immunoglobulin A Deficiency 1

Immunoglobulin A Deficiency

Selective Iga Deficiency Disease

Selective Immunoglobulin A Deficiency

IGAD1

Immunoglobulin A, Selective Deficiency Of

Iga, Selective Deficiency Of

Gamma-A-Globulin, Selective Deficiency Of

Selective Iga Immunodeficiency

Selective Iga Deficiency

Iga Deficiency Selective

Hermansky-Pudlak Syndrome 1

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

HPS1

Delta Storage Pool Disease

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial

Hermansky-Pudlak Syndrome, Type 1

Platelet Storage Pool Deficiency

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SEC31B VGNC VGNC:77293
Canis familiaris SEC31B VGNC VGNC:45977
Rattus norvegicus SEC31B RGD RGD:1598329
Mus musculus SEC31B MGD MGI:2685187
Bos taurus SEC31B VGNC VGNC:34418
Felis catus SEC31B VGNC VGNC:64972