2. Gene
  3. L3MBTL1 - L3MBTL histone methyl-lysine binding protein 1 Gene

L3MBTL1 - L3MBTL histone methyl-lysine binding protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：L3MBTL 组蛋白甲基赖氨酸结合蛋白 1

种属: Homo sapiens

同用名: L3MBTL; ZC2HC3; H-L(3)MBT; dJ138B7.3

基因 ID: 26013 | 基因类型: protein coding

关于 L3MBTL1

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:43,507,697-43,550,954 (from NCBI)

This gene has 33 transcripts (splice variants), 209 orthologues and 18 paralogues. Broad expression in testis (RPKM 4.3), brain (RPKM 2.6) and 23 other tissues.

功能概要

该基因代表多梳组基因。编码的蛋白质可能通过染色质修饰来调节基因活性。编码的蛋白质也可能是有丝分裂所必需的。已经识别出编码不同亚型的选择性剪接转录本变体。[RefSeq 提供，2010 年 9 月]

This gene represents a polycomb group gene. The encoded protein functions to regulate gene activity, likely via chromatin modification. The encoded protein may also be necessary for mitosis. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]

L3MBTL1 基因产物(9)

mRNA Protein Name
NM_001377303.1 NP_001364232.1 lethal(3)malignant brain tumor-like protein 1 isoform 3
NM_001377306.1 NP_001364235.1 lethal(3)malignant brain tumor-like protein 1 isoform 4
NM_001377307.1 NP_001364236.1 lethal(3)malignant brain tumor-like protein 1 isoform 5
NM_001377308.1 NP_001364237.1 lethal(3)malignant brain tumor-like protein 1 isoform 6
NM_001377309.1 NP_001364238.1 lethal(3)malignant brain tumor-like protein 1 isoform 7
NM_001377310.1 NP_001364239.1 lethal(3)malignant brain tumor-like protein 1 isoform 8
NM_001377311.1 NP_001364240.1 lethal(3)malignant brain tumor-like protein 1 isoform 9
NM_015478.7 NP_056293.4 lethal(3)malignant brain tumor-like protein 1 isoform 1
NM_032107.5 NP_115479.4 lethal(3)malignant brain tumor-like protein 1 isoform 2

L3MBTL1 蛋白结构

MBT

MBT: mbt repeat (310 - 382)

MBT

MBT: mbt repeat (417 - 486)

MBT

MBT: mbt repeat (521 - 590)

zf-C2HC

zf-C2HC: Zinc finger, C2HC type (620 - 649)

  • 0
  • 200
  • 400
  • 600
  • 840 a.a.
蛋白主名 其他名称

lethal(3)malignant brain tumor-like protein 1

L3MBTL1, histone methyl-lysine binding protein

关联疾病

疾病名称 别名
Brain Cancer

Adult Brain Tumor

Malignant Neoplasm Of Brain

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary
Bardet-Biedl Syndrome 2

BBS2

Bardet-Biedl Syndrome

Bardet-Biedl Syndrome, Type 2

Bbs
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15839 UNC 669 Inhibitor 99.88% 否
HY-16510 UNC926 Inhibitor 99.82% 否
HY-16510A UNC926 hydrochloride Inhibitor / 否
HY-RS07484 L3MBTL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus L3MBTL1 MGD MGI:2676663
Canis familiaris L3MBTL1 VGNC VGNC:54652
Rattus norvegicus L3MBTL1 RGD RGD:1307316
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z