1. Gene
  2. F7 - coagulation factor VII Gene

F7 - coagulation factor VII Gene

种属: Rattus norvegicus

基因 ID: 260320 | 基因类型: protein coding

关于 F7

功能概要

Enables endopeptidase activity and signaling receptor binding activity. Involved in several processes, including response to anticoagulant; response to peptide hormone; and response to thyroxine. Located in extracellular space and vesicle. Used to study asthma; diabetes mellitus; and type 2 diabetes mellitus. Biomarker of several diseases, including bilirubin metabolic disorder; familial hyperlipidemia; hypertension; hypothyroidism; and prothrombin deficiency. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebral infarction; diabetes mellitus (multiple); factor VII deficiency; and obesity. Orthologous to human F7 (coagulation factor VII). [provided by Alliance of Genome Resources, Apr 2022]

F7 基因产物(1)

mRNA Protein Name
NM_152846.2 NP_690059.1 coagulation factor VII precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables endopeptidase activity IDA
IDA: 通过直接分析推断
12757778 RGD
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
18315926 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
14724430 RGD
involved in circadian rhythm IEP
IEP: 通过表达模式推断
2607889 RGD
involved in positive regulation of blood coagulation IDA
IDA: 通过直接分析推断
12757778 RGD
involved in response to 2,3,7,8-tetrachlorodibenzodioxine IEP
IEP: 通过表达模式推断
10901669 RGD
involved in response to Thyroid stimulating hormone IEP
IEP: 通过表达模式推断
21382270 RGD
involved in response to astaxanthin IDA
IDA: 通过直接分析推断
22309505 RGD
involved in response to carbon dioxide IEP
IEP: 通过表达模式推断
26855512 RGD
involved in response to cholesterol IDA
IDA: 通过直接分析推断
15670042 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
20838740 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
2821645 RGD
involved in response to genistein IEP
IEP: 通过表达模式推断
20838740 RGD
involved in response to growth hormone IEP
IEP: 通过表达模式推断
7493602 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
18336749 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
9155722 RGD
involved in response to nutrient levels IDA
IDA: 通过直接分析推断
11880553 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
11776312 RGD
involved in response to thyroid hormone IEP
IEP: 通过表达模式推断
21382270 RGD
involved in response to thyrotropin-releasing hormone IEP
IEP: 通过表达模式推断
21382270 RGD
involved in response to thyroxine IEP
IEP: 通过表达模式推断
21382270 RGD
involved in response to vitamin K IEP
IEP: 通过表达模式推断
3379837 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
14724430 RGD
located in vesicle IDA
IDA: 通过直接分析推断
4307182 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

coagulation factor VII

serum prothrombin conversion accelerator

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F7 NCBI NCBI:2155
Macaca fascicularis F7 NCBI NCBI:102121077
Mus musculus F7 NCBI NCBI:14068
Macaca mulatta F7 NCBI NCBI:721933