2. Gene
  3. DNM3 - dynamin 3 Gene

DNM3 - dynamin 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：动力 3

种属: Homo sapiens

同用名: Dyna III

基因 ID: 26052 | 基因类型: protein coding

关于 DNM3

Cytogenetic location: 1q24.3 Genomic coordinates (GRCh38): 1:171,841,498-172,418,466 (from NCBI)

This gene has 9 transcripts (splice variants), 191 orthologues and 6 paralogues. Biased expression in brain (RPKM 10.0), adrenal (RPKM 2.5) and 8 other tissues.

功能概要

该基因编码与微管相关并参与囊泡运输的三磷酸鸟苷 (GTP) 结合蛋白家族的成员。编码的蛋白质在巨核细胞的发育中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 5 月]

This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

DNM3 基因产物(6)

mRNA Protein Name
NM_001136127.3 NP_001129599.1 dynamin-3 isoform b
NM_001278252.2 NP_001265181.1 dynamin-3 isoform c
NM_001350204.2 NP_001337133.1 dynamin-3 isoform d
NM_001350205.2 NP_001337134.1 dynamin-3 isoform e
NM_001350206.2 NP_001337135.1 dynamin-3 isoform f
NM_015569.5 NP_056384.2 dynamin-3 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
26302298 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15252009 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DNM3 蛋白结构

Dynamin_N

Dynamin_N: Dynamin family (34 - 207)

Dynamin_M

Dynamin_M: Dynamin central region (216 - 505)

PH

PH: PH domain (526 - 626)

GED

GED: Dynamin GTPase effector domain (655 - 744)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 869 a.a.
蛋白主名 其他名称

dynamin-3

T-dynamin

DNM3 抗体

目录号 产品名 应用 反应物种
HY-P83234 Dynamin 3 Antibody (YA2979) WB Human, Mouse

关联疾病

疾病名称 别名
Autosomal Dominant Optic Atrophy Plus Syndrome

Cerebellar Ataxia-Areflexia-Pes Cavus-Optic Atrophy-Sensorineural Hearing Loss Syndrome

Capos Syndrome

Optic Atrophy With Or Without Deafness, Ophthalmoplegia, Myopathy, Ataxia, And Neuropathy

Optic Atrophy-Deafness-Polyneuropathy-Myopathy Syndrome

Cerebellar Ataxia, Areflexia, Pes Cavus, Optic Atrophy And Sensorinural Hearing

Cerebellar Ataxia, Areflexia, Pes Cavus, Optic Atrophy And Sensorinural Hearing Loss

Capos

Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss

Dominant Optic Atrophy Plus Syndrome

Dominant Optic Atrophy, Deafness, Ptosis, Ophthalmoplegia, Dystaxia, And Myopathy

Optic Atrophy - Deafness- Polyneuropathy - Myopathy

Treft-Sanborn-Carey Syndrome

Doa+

Optic Atrophy-Hearing Loss-Polyneuropathy-Myopathy Syndrome

Cerebellar Ataxia-Areflexia-Pes Cavus-Optic Atrophy-Sensorineural Deafness Syndrome

Optic Atrophy Autosomal Dominant

Treft Sanborn Carey Syndrome
Neuropathy, Hereditary Sensory, Type Id

HSN1D

Hereditary Sensory Neuropathy Type 1d

Neuropathy, Hereditary Sensory, Type 1d

Neuropathy, Hereditary Sensory, 1d

Hereditary Sensory Neuropathy Type Id

Neuropathy, Sensory, Hereditary, Type Id
Wiskott-Aldrich Syndrome

WAS

Eczema-Thrombocytopenia-Immunodeficiency Syndrome

Immunodeficiency 2

Aldrich Syndrome

Imd2

Wiskott-Aldrich Syndrome 1

Was1

Wiskott Syndrome

Wiskott Aldrich Syndrome

Eczema Thrombocytopenia Immunodeficiency Syndrome

Imd 2
Cholera

Vibrio Cholerae Infection

Cholera - Vibrio Cholerae

Cholera Due To Vibrio Cholerae

Vibrio Cholerae

Cholera Syndrome

Asiatic Cholera

Epidemic Cholera
Alstrom Syndrome

ALMS

Alström Syndrome

Alss

Alstrom-Hallgren Syndrome

Alstroem Syndrome
Sezary'S Disease

Sezary Syndrome

Sézary Syndrome

Sezary'S Lymphoma

Sezary Disease

Sezary Erythroderma

Sezary Lymphoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03906 DNM3 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris DNM3 VGNC VGNC:40034
Felis catus DNM3 VGNC VGNC:107868
Rattus norvegicus DNM3 RGD RGD:727949
Macaca mulatta DNM3 VGNC VGNC:71928
Bos taurus DNM3 VGNC VGNC:106714
Mus musculus DNM3 MGD MGI:1341299
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z