2. Gene
  3. Dab1 - DAB adaptor protein 1 Gene

Dab1 - DAB adaptor protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 266729 | 基因类型: protein coding

关于 Dab1

功能概要

Enables phosphatidylinositol 3-kinase binding activity. Involved in midgut development; nervous system development; and response to xenobiotic stimulus. Located in several cellular components, including brush border; neuronal cell body; and postsynaptic density. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Orthologous to human DAB1 (DAB adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Dab1 基因产物(2)

mRNA Protein Name
NM_001411819.1 NP_001398748.1 disabled homolog 1
NM_153621.2 NP_705885.1 disabled homolog 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphatidylinositol 3-kinase binding IPI
IPI: 通过物理相互作用推断
12882964 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebral cortex development IEP
IEP: 通过表达模式推断
20368265 RGD
involved in cerebral cortex radially oriented cell migration IMP
IMP: 通过突变表型推断
18160654 RGD
involved in midgut development IEP
IEP: 通过表达模式推断
19946030 RGD
involved in neuron migration IDA
IDA: 通过直接分析推断
12882964 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
10436054 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
19946030 RGD
located in brush border IDA
IDA: 通过直接分析推断
19946030 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
14961563 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

disabled homolog 1

DAB1, reelin adaptor protein

Dab, reelin signal transducer, homolog 1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03510 DAB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03840 DNAAF3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09781 OMA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19317 Dab1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25808 Dab1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dab1 NCBI NCBI:1600
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