2. Gene
  3. Alkbh5 - alkB homolog 5, RNA demethylase Gene

Alkbh5 - alkB homolog 5, RNA demethylase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Abh5; Ofoxd; E130207K11

基因 ID: 268420 | 基因类型: protein coding

关于 Alkbh5

功能概要

Enables mRNA N6-methyladenosine dioxygenase activity. Involved in oxidative single-stranded RNA demethylation; regulation of mRNA stability; and spermatogenesis. Located in nuclear speck. Is expressed in brain. Orthologous to human ALKBH5 (alkB homolog 5, RNA demethylase). [provided by Alliance of Genome Resources, Apr 2022]

Alkbh5 基因产物(1)

mRNA Protein Name
NM_172943.4 NP_766531.2 RNA demethylase ALKBH5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables lysophospholipase activity IDA
IDA: 通过直接分析推断
16818490 MGI
enables mRNA N6-methyladenosine dioxygenase activity IMP
IMP: 通过突变表型推断
29279410 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of gamma-delta T cell proliferation IMP
IMP: 通过突变表型推断
35939687 MGI
involved in mRNA destabilization IMP
IMP: 通过突变表型推断
36859428 MGI
involved in regulation of mRNA stability IMP
IMP: 通过突变表型推断
29279410 MGI
involved in spermatogenesis IMP
IMP: 通过突变表型推断
23177736 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear speck IMP
IMP: 通过突变表型推断
29279410 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

RNA demethylase ALKBH5

alkB, alkylation repair homolog 5

alkylated DNA repair protein alkB homolog 5

alpha-ketoglutarate-dependent dioxygenase alkB homolog 5

oxoglutarate and iron-dependent oxygenase domain containing

probable alpha-ketoglutarate-dependent dioxygenase ABH5

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12304 IOX1 Inhibitor 99.89% 否
HY-155489 DDO-2728 98.55% 否
HY-165422 ALKBH5-IN-3 Inhibitor 99.63% 否
HY-172158 ALKBH5-IN-5 Inhibitor 99.65% 否
HY-RS00606 ALKBH5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-173020 W23-1006 / 否
HY-W173146 ALKBH5-IN-4 ≥95.0% 否
HY-148933 ALKBH5-IN-2 Inhibitor / 否
HY-149145 Ena15 / 否
HY-170668 DDO-02267 Inhibitor / 否
HY-RS16695 Alkbh5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23130 Alkbh5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Alkbh5 NCBI NCBI:54890
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