2. Gene
  3. Setx - senataxin Gene

Setx - senataxin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: AOA2; Als4; Sen1; SCAR1; mKIAA0625; A130090N03; A930037J23Rik

基因 ID: 269254 | 基因类型: protein coding

关于 Setx

功能概要

Predicted to enable RNA binding activity; identical protein binding activity; and transcription termination site sequence-specific DNA binding activity. Acts upstream of or within circadian rhythm and termination of RNA polymerase II transcription. Predicted to be located in several cellular components, including growth cone; intercellular bridge; and nuclear lumen. Predicted to be active in nuclear body. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4 and ataxia with oculomotor apraxia type 2. Orthologous to human SETX (senataxin). [provided by Alliance of Genome Resources, Apr 2022]

Setx 基因产物(1)

mRNA Protein Name
NM_198033.2 NP_932150.2 probable helicase senataxin
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22767893 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within circadian rhythm IMP
IMP: 通过突变表型推断
22767893 MGI
acts upstream of or within termination of RNA polymerase II transcription IMP
IMP: 通过突变表型推断
22767893 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

probable helicase senataxin

SEN1 homolog

amyotrophic lateral sclerosis 4 homolog

amyotrophic lateral sclerosis 4 protein homolog

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12752 SETX Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22320 Setx Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28842 Setx Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Setx NCBI NCBI:23064
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