2. Gene
  3. GPR15 - G protein-coupled receptor 15 Gene

GPR15 - G protein-coupled receptor 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白偶联受体 15

种属: Homo sapiens

同用名: BOB

基因 ID: 2838 | 基因类型: protein coding

关于 GPR15

Cytogenetic location: 3q11.2 Genomic coordinates (GRCh38): 3:98,531,978-98,534,681 (from NCBI)

This gene has 1 transcript (splice variant), 120 orthologues and 7 paralogues.

功能概要

该基因编码一种 G 蛋白偶联受体，该受体充当 1 型和 2 型人类免疫缺陷病毒的趋化因子受体。编码的蛋白质定位于细胞膜。[RefSeq 提供，2012 年 11 月]

This gene encodes a G protein-coupled receptor that acts as a Chemokine Receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]

GPR15 基因产物(1)

mRNA Protein Name
NM_005290.4 NP_005281.1 G-protein coupled receptor 15
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
28900043 GOA
enables coreceptor activity IDA
IDA: 通过直接分析推断
15650194 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
28936214 GOA
enables virus receptor activity IDA
IDA: 通过直接分析推断
15650194 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
28900043 GOA
involved in angiogenesis IMP
IMP: 通过突变表型推断
28386128 GOA
involved in symbiont entry into host cell IDA
IDA: 通过直接分析推断
15650194 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11696454 GOA
located in endosome IDA
IDA: 通过直接分析推断
28615320 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
28615320 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GPR15 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (50 - 302)

  • 0
  • 100
  • 200
  • 300
  • 360 a.a.
蛋白主名 其他名称

G-protein coupled receptor 15

brother of Bonzo

GPR15 抗体

目录号 产品名 应用 反应物种
HY-P84356 GPR15 Antibody (YA4053) ICC/IF, FC, ELISA Human

关联疾病

疾病名称 别名
Human Immunodeficiency Virus Type 1

Aids

Hiv/Aids

Aids, Delayed/Rapid Progression To

Hiv-1, Susceptibility To

Hiv-1 Viremia, Susceptibility To

Human Immunodeficiency Virus Type 1, Susceptibility To

Hiv-1

Aids, Slow Progression To

Rapid Progression To Aids From Hiv1 Infection

Hiv1 Infection, Resistance To

Hiv1 Infection

Hiv-1 Viremia

Aids, Resistance To

Aids, Rapid Progression To

Hiv/Aids, Susceptibility To

Hiv-1, Resistance To

Hiv1, Resistance To

Hiv1

Hiv-1 Disease, Delayed Progression Of

Hiv-1 Disease, Rapid Progression Of

Hiv Infection, Resistance To

Hiv Type 1, Susceptibility To

Hiv Type 1

Hiv-1 Infection

Human Immunodeficiency Virus I Infection

Acquired Immunodeficiency Syndrome

Hiv-Infection/Aids
Gray Zone Lymphoma

B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma And Classical Hodgkin Lymphoma
Thymus Basaloid Carcinoma

Basaloid Carcinoma Of The Thymus

Thymic Basaloid Carcinoma
Mediastinal Gray Zone Lymphoma

Mediastinal B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma And Classical Hodgkin Lymphoma
Mediastinal Malignant Lymphoma

Lymphoma Of Mediastinum

Mediastinal Lymphoma
Immune Deficiency Disease

Immunodeficiency

Primary Immunodeficiency

Primary Immunodeficiency Disease

Immunologic Deficiency Syndromes

Hypoimmunity

Immune Deficiency Disorder

Immunodeficiency Syndrome

Immune Disorder

Primary Immune Deficiency Disorder

Immune System Diseases

Human Immunodeficiency Virus Infection

Hiv - [Human Immunodeficiency Virus Infection]

Hiv Positive Nos

Hiv Disease

Acquired Immune Deficiency Syndrome-Related Complex

Aids-Like Syndrome

Aids-Related Complex Nos

Arc - [Aids-Related Complex]

Immunodeficiency Due To Human Immunodeficiency Virus Infection

Unspecified Human Immunodeficiency Virus Disease

Hiv Disease Nos

Human Immunodeficiency Virus Positive Nos

Hiv Nos

Deficiency Of Complement Initial Pathway

Deficiency Of Complement Terminal Pathway

Cfdd - [Complement Factor D Deficiency]

Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency

Nonfamilial Hypogammaglobulinaemia

Common Variable Immune Deficiency

Nonfamilial Agammaglobulinaemia

Common Variable Agammaglobulinaemia

Agammaglobulinaemia Nos

Agammaglobulinaemia Antibody Deficiency Syndrome

Hypogammaglobulinaemia Antibody Deficiency Syndrome

Acquired Agammaglobulinaemia Nos

Hypogammaglobulinaemia Nos

Hyper Igm
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P2196A ELA-32(human) TFA Agonist 99.93% 否
HY-RS05668 GPR15 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19438 Gpr15 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25929 Gpr15 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta GPR15 VGNC VGNC:73125
Felis catus GPR15 VGNC VGNC:67416
Mus musculus GPR15 MGD MGI:1918473
Rattus norvegicus GPR15 RGD RGD:1306639
Bos taurus GPR15 VGNC VGNC:29557
Canis familiaris GPR15 VGNC VGNC:41404
Others GPR15 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z