TAFA3 - TAFA chemokine like family member 3 Gene

中文名称：TAFA 趋化因子样家族成员 3

种属: Homo sapiens

同用名: TAFA-3; FAM19A3

关于 TAFA3

功能概要

该基因是 TAFA 家族的成员，该家族由五个高度同源的基因组成，编码小的分泌蛋白。这些蛋白质在固定位置包含保守的半胱氨酸残基，并且与 CC 趋化因子家族的成员 MIP-1alpha 有远缘关系。 TAFA 蛋白主要在大脑的特定区域表达，并被假定作为大脑特异性趋化因子或神经因子发挥作用，充当免疫和神经细胞的调节剂。已经观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 11 月]

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]