1. Gene
  2. Wnk4 - WNK lysine deficient protein kinase 4 Gene

Wnk4 - WNK lysine deficient protein kinase 4 Gene

种属: Rattus norvegicus

同用名: Ac2-059; Prkwnk4

基因 ID: 287715 | 基因类型: protein coding

关于 Wnk4

功能概要

Enables protein serine/threonine kinase activity. Involved in negative regulation of sodium ion transport and protein phosphorylation. Located in cytosol and membrane. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in hypertension and pseudohypoaldosteronism. Orthologous to human WNK4 (WNK lysine deficient protein kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Wnk4 基因产物(1)

mRNA Protein Name
NM_175579.3 NP_783169.2 serine/threonine-protein kinase WNK4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16083423 RGD
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
16083423 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of sodium ion transport IDA
IDA: 通过直接分析推断
16204408 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
16083423 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
25515571 RGD
located in membrane IDA
IDA: 通过直接分析推断
25515571 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase WNK4

WNK4 Ser/Thr kinase

protein kinase lysine-deficient 4

protein kinase with no lysine 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wnk4 NCBI NCBI:65266